EFFECTS OF UMBILICAL CORD MILKING ON HEMATOLOGICAL PARAMETERS IN TERM NEONATES: A CASE CONTROL STUDY IN A TERTIARY CARE HOSPITAL

Ashwini Sankannavar, B. Masali, Kulkarni Poornima Prakash
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Abstract

Delayed cord clamping (DCC) and Umbilical cord milking (UCM) are the two methods of placental transfusion. Bothinterventions improve hemoglobin, are safe with no risk of polycythemia and hyperbilirubinemia. UCM is benefi cial in situation were DCC is not feasible or contraindicated.Objectives. 1) Comparison of UCM and DCC on following hematological parameters in term neonates- Cord Hemoglobinat birth, Hemoglobin, Hematocrit and Bilirubin at 48 hours of life. 2) To compare Hb and ferritin levels of infants born withUCM to that of DCC at 6 weeks of age.Material and methods. A Prospective Case- Control Study. Newborns delivered by normal vaginal and elective lower segmentcesarean section underwent DCC. Neonates in whom DCC was not feasible underwent UCM. 56 neonates in each group were followed up to 6 weeks. Cord hemoglobin at birth, hemoglobin, hematocrit and bilirubin were sent at 48 hours, and during 6 weeks of life, Hb and serum ferritin was estimated in both groups and compared.Results: At 48 hours, mean hemoglobin is 18.75 and 19.38 g/dL, mean hematocrit is 52.20 and 53.94 %, and mean totalbilirubin is 11.56 and 10.39 mg/dL in the DCC and UCM groups, respectively. Mean hemoglobin at 6 weeks is 11.37 and 11.6 gm/dL and mean serum ferritin is 207.2 and 252.63 mcg/L in the DCC and UCM groups, respectively. No increase in the incidence of neonatal jaundice or polycythemia was observed in either group.Conclusion. Both the methods of placental transfusions DCC and UCM are equally eff ective and have comparable benefi ton hematological parameters in full term neonates at 48 hours of life and at 6 weeks of life.
脐带挤奶对足月新生儿血液学参数的影响:一家三级医院的病例对照研究
延迟脐带夹闭(DCC)和脐带挤奶(UCM)是胎盘输血的两种方法。这两种方法都能改善血红蛋白,而且安全,没有多血症和高胆红素血症的风险。在 DCC 不可行或有禁忌症的情况下,UCM 是有益的。1)比较 UCM 和 DCC 对足月新生儿以下血液参数的影响--出生时的脐带血红蛋白、出生 48 小时时的血红蛋白、血细胞比容和胆红素。2) 比较 6 周大时 UCM 新生儿与 DCC 新生儿的血红蛋白和铁蛋白水平。前瞻性病例对照研究。经正常阴道分娩和选择性下段剖宫产的新生儿均接受了 DCC。无法进行 DCC 的新生儿接受 UCM。每组 56 名新生儿均接受了长达 6 周的随访。两组新生儿出生时的脐带血红蛋白、48 小时时的血红蛋白、血细胞比容和胆红素以及出生后 6 周内的血红蛋白和血清铁蛋白均进行了估算和比较:结果:48 小时时,DCC 组和 UCM 组的平均血红蛋白分别为 18.75 和 19.38 g/dL,平均血细胞比容分别为 52.20 和 53.94 %,平均总胆红素分别为 11.56 和 10.39 mg/dL。DCC 组和 UCM 组 6 周时的平均血红蛋白分别为 11.37 和 11.6 克/分升,平均血清铁蛋白分别为 207.2 和 252.63 微克/升。两组新生儿黄疸或多血症的发生率均未增加。在足月新生儿出生 48 小时和 6 周时,DCC 和 UCM 两种胎盘输血方法同样有效,且血液学参数的益处相当。
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