EFFECT OF ADDITION OF DEXAMETHASONE TO ROPIVACAINE ON POST-OPERATIVE ANALGESIA IN ULTRASOUND-GUIDED TRANSVERSE ABDOMINIS PLANE BLOCK FOR ANTERIOR ABDOMINAL WALL HERNIA REPAIR

Pooja Garhwal, Shobha Parashar, S. M. Mitharwal, Pooja Vijay
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Abstract

Objective: The objective of the present study was to evaluate the adjuvant effect of dexamethasone to Ropivacaine in ultrasound-guided transverse abdominal plan block for anterior abdominal wall hernia repair. Methods: A single-blind randomized control trial was conducted by selecting patients undergoing anterior abdominal wall hernia and dividing them into two groups with Group A: received a total of 50 mL of 0.2% Ropivacaine (48 mL) with normal saline (2 mL) and Group B received a total 50 mL of 0.2% Ropivacaine (48 mL) with 8 mg dexamethasone (2 mL). Outcome was assessed on the basis of visual analog scale (VAS), the requirement of rescue analgesia, and adverse events. Results: Twenty-seven patients were recruited in each group, Group A and Group B had an average pain-free interval of 11.85±2.82 and 8.07±2.51, respectively (p<0.001). Mean VAS was lower in Group B at the end of 2 h (p<0.05). Both the groups had similar side effects with no significant difference. Total analgesia dose required in Groups B and A was 75 and 96 mg, respectively (p<0.001). Conclusion: A combination of 0.2% Ropivacaine (48 mL) with 8 mg dexamethasone (2 mL) significantly reduces the VAS in post-operative pain along with reduced quantity and frequency of rescue analgesia.
在罗哌卡因中加入地塞米松对超声引导下经腹横肌平面阻滞腹壁前疝修补术术后镇痛的影响
研究目的本研究的目的是评估地塞米松与罗哌卡因在超声引导下经腹平面阻滞治疗前腹壁疝修补术中的辅助效果:方法:选择腹壁前疝患者进行单盲随机对照试验,将其分为两组,A组接受总计50 mL的0.2%罗哌卡因(48 mL)和生理盐水(2 mL),B组接受总计50 mL的0.2%罗哌卡因(48 mL)和8 mg地塞米松(2 mL)。结果根据视觉模拟量表(VAS)、镇痛抢救需求和不良反应进行评估:A 组和 B 组的平均无痛间隔时间分别为(11.85±2.82)和(8.07±2.51)(P<0.001)。2 小时结束时,B 组的平均 VAS 值更低(P<0.05)。两组的副作用相似,无明显差异。B 组和 A 组所需的镇痛总剂量分别为 75 毫克和 96 毫克(P<0.001):结论:0.2% 罗哌卡因(48 毫升)与 8 毫克地塞米松(2 毫升)联合使用可显著降低术后疼痛的 VAS 值,同时减少镇痛抢救的数量和频率。
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