The impact of menopause on antidepressant response: an explorative analysis from a real-world study

IF 3.2 3区医学 Q2 PSYCHIATRY

Archives of Women's Mental Health Pub Date : 2024-04-08 DOI:10.1007/s00737-024-01465-x

Matteo Carminati, Valentina Fazio, Melania Maccario, Raffaella Zanardi

引用次数: 0

Abstract

This study endeavors to deepen our understanding of the subject matter by exploring, within a real-world sample, the impact of menopausal status on the antidepressant treatments response. The whole sample included a total of 447 patients, 156 male and 291 female, 110 pre-menopause and 181 post-menopause. In our sample post-menopause women showed a worse response to antidepressants than pre-menopause women (p = 0.006), and this difference seems to be unrelated to age or brain aging.

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更年期对抗抑郁药反应的影响：一项真实世界研究的探索性分析。

本研究通过在实际样本中探讨更年期状态对抗抑郁治疗反应的影响，努力加深我们对这一主题的理解。整个样本共包括 447 名患者，其中男性 156 人，女性 291 人，绝经前 110 人，绝经后 181 人。在我们的样本中，绝经后妇女对抗抑郁药物的反应比绝经前妇女差（p = 0.006），这种差异似乎与年龄或大脑老化无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Women's Mental Health 医学-精神病学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.