A Rare Case of Sjogren’s Syndrome with Polymyositis: A Case Report

Namra Gohil, Apurva Patel, Aasvi V Gohil, D. Solanki
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Abstract

Sjogren’s syndrome (SS) is an autoimmune chronic inflammatory disorder affecting women in their fourth to sixth decade, affecting gastrointestinal, and musculoskeletal systems. A 35-year-old female with SS with polymyositis (PM) presented with symptoms of weakness in all four limbs, difficulty in sitting, rising, swallowing solid foods, vomiting, and difficulty in climbing stairs. She was diagnosed with SS in 2018 and was treated with prednisolone, Vitamin D, calcium, pyridoxine, methylcobalamin, artificial tears, pilocarpine, and painkillers. However, a muscle biopsy was never done. The data were collected from the patient’s file along with her consent when she came for follow-up. A muscle biopsy was done at our center to confirm the diagnosis of PM. The patient was prescribed IV prednisolone and other symptomatic treatment until symptoms resolved and was discharged with oral drugs when they were manageable. The diagnosis of primary SS along with PM is a rare occurrence. Although it does not change the treatment plan much, its diagnosis is very important for managing any complications that may arise from it. Patients’ noncompliance and loss of follow-up can create issues in the treatment. Such cases help in forming the guidelines for the future and restructuring the classification of autoimmune conditions.
一个罕见的 Sjogren's 综合征合并多发性肌炎病例:病例报告
斯约格伦综合征(SS)是一种自身免疫性慢性炎症性疾病,好发于四至六十岁的女性,影响胃肠道和肌肉骨骼系统。一名35岁的女性患者患有SS合并多发性肌炎(PM),出现四肢无力、坐立困难、起立困难、吞咽固体食物困难、呕吐、爬楼梯困难等症状。她于2018年被确诊为SS,并接受了泼尼松龙、维生素D、钙、吡哆醇、甲基钴胺、人工泪液、皮洛卡品和止痛药等治疗。但从未进行肌肉活检。在患者前来复诊时,我们从她的档案中收集了相关数据,并征得了她的同意。本中心对患者进行了肌肉活检,以确诊其为 PM。患者接受了静脉注射泼尼松龙和其他对症治疗,直到症状缓解,并在症状可控时以口服药物出院。原发性 SS 合并 PM 的诊断很少见。虽然它不会对治疗方案造成太大的改变,但其诊断对于处理可能由此引发的并发症非常重要。患者不配合治疗和失去随访可能会给治疗带来问题。此类病例有助于为未来制定指导方针,并调整自身免疫性疾病的分类。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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34
审稿时长
13 weeks
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