COMPARATIVE ANALYSIS OF CONSUMPTION AND PURPOSE OF ANTIEPILEPTIC DRUGS RELEASED FOR FREE OR WITH A DISCOUNT

Abstract

Aim - conduct a comparative analysis of the consumption of free or discounted antiepileptic drugs for the period 2017-2021 at the regional level. Material and methods. The information base was made up of the works of domestic and foreign scientists in the field of preferential drug provision, as well as regulatory and organizational documentation on pharmaceutical activities. Preferential prescriptions issued for the period from 2017 to 2021 were analyzed. in the Oryol region. The DDD/ATC methodology was used to estimate consumption. Results. As a result of the study, it was revealed that preferential antiepileptic drugs are mainly taken by people aged 40-64 years. It has been established that if in 2017-2018 antiepileptic drugs were consumed more by women, then in 2019-2021 by men. Most of the consumers of antiepileptic drugs are federal beneficiaries, mostly disabled people of group II. The highest value of consumption among the top 5 INNs of antiepileptic drugs during the study period is observed for Phenobarbital. For drugs Valproic acid, Topiramate and Carbamazepine is characterized by the dynamics of increasing consumption throughout the study period. For benzobarbital, a pattern of consumption stability was revealed. Conclusions. Analysis of the structure of consumption of antiepileptic drugs within the framework of the program of subsidized drug provision of the population using the DDD/ATC methodology makes it possible to identify objective data on the dynamics of consumption of antiepileptic drugs of various generations. In order to reduce the consumption of drugs with an unfavorable safety profile, it is necessary to conduct training seminars for doctors of the relevant profile.