Mesenchymal Stem Cells Ameliorate Lipid Metabolism while Reducing Blood Glucose in Streptozotocin (STZ)-Induced Diabetes Mellitus and High Fat Diet Induced Obesity

Abstract

Background: Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine and have beneficial effects to treat different pathologies, including neurological disorders, cardiac ischemia, diabetes, and bone and cartilage diseases, Fortunately, MSCs, known for their lower immunogenicity and self-renewal ability, can be induced into insulin-producing cells (IPCs) and have attracted significant attention for the treatment of DM. Importantly.