Exploring Adolescent and Young Adult Cancer Survivors' Experience with Cancer Treatment-Related Symptoms: A Qualitative Analysis of Semi-Structured Interviews.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-18 DOI:10.1089/jayao.2024.0053

Robert Knoerl, Katherine Grandinetti, Liat Smener, Emily Doll, Leslie A Fecher, N. L. Henry, Yasmin Karimi, Kristen Pettit, Scott Schuetze, Emily Walling, Anao Zhang, Debra Barton

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引用次数: 0

Abstract

Purpose: Few studies have specifically targeted symptom management interventions for adolescent and young adult (AYA) cancer survivors. A greater understanding of AYA cancer survivors' experiences with cancer treatment-related symptoms would help develop age-appropriate oncology symptom management interventions. The purpose of this qualitative analysis was to explore AYA cancer survivors' experience with cancer treatment-related symptoms. Methods: Nineteen post-treatment AYA cancer survivors (18-39 years old) who self-reported moderate-severe cancer treatment-related symptom severity participated in video conferencing or telephone interviews. The questions in the interview guide queried participants to share their experience with cancer treatment-related symptoms. Inductive content analysis was used to identify themes from the interviews. Results: The themes that emerged from the interviews included (1) cancer treatment-related symptoms negatively affected AYA cancer survivors' quality of life (e.g., symptoms served as a reminder of cancer recurrence possibility); (2) AYA cancer survivors' attitudes and feelings about communicating cancer treatment-related symptom concerns to clinicians (e.g., patient-clinician communication was bolstered when AYAs perceived that symptoms were being taken seriously); (3) AYA cancer survivors are interested in oncology symptom management clinical trials, but logistical challenges are barriers to participation; and (4) AYA cancer survivors are interested in nonpharmacological treatments for symptom management. Conclusion: Results highlight the burden of cancer treatment-related symptoms on day-to-day life among post-treatment AYA cancer survivors. Future work is needed to identify nonpharmacological symptom management interventions, strategies to improve patient-clinician communication about symptoms, and strategies to increase the visibility and accessibility of symptom management clinical trials for AYA cancer survivors.

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探索青少年和年轻成人癌症幸存者对癌症治疗相关症状的体验：半结构式访谈的定性分析。

研究目的很少有研究专门针对青少年癌症幸存者的症状管理干预措施。更深入地了解青少年癌症幸存者在癌症治疗相关症状方面的经历将有助于开发适合其年龄的肿瘤症状管理干预措施。本定性分析旨在探讨青少年癌症幸存者对癌症治疗相关症状的体验。研究方法19 名治疗后的亚裔癌症幸存者（18-39 岁）参加了视频会议或电话访谈，他们自述癌症治疗相关症状的严重程度为中度-重度。访谈指南中的问题要求参与者分享他们在癌症治疗相关症状方面的经历。采用归纳式内容分析法确定访谈主题。结果访谈中出现的主题包括：（1）癌症治疗相关症状对青壮年癌症幸存者的生活质量产生了负面影响（例如，症状提醒他们癌症复发的可能性）；（2）青壮年癌症幸存者在与临床医生沟通癌症治疗相关症状问题时的态度和感受（例如，患者与医生之间的沟通有助于提高他们的生活质量）；（3）青壮年癌症幸存者在与临床医生沟通癌症治疗相关症状问题时的态度和感受（例如，患者与医生之间的沟通有助于提高他们的生活质量）、(3) 亚裔癌症幸存者对肿瘤症状管理临床试验感兴趣，但后勤方面的挑战阻碍了他们的参与；以及 (4) 亚裔癌症幸存者对症状管理的非药物治疗感兴趣。结论研究结果突显了与癌症治疗相关的症状给治疗后的亚裔癌症幸存者日常生活带来的负担。今后的工作需要确定非药物症状管理干预措施、改善患者与医生就症状进行沟通的策略，以及提高亚裔癌症幸存者症状管理临床试验的可见性和可及性的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.