The effect of osteopathic manipulative treatment on quality of life in patients with cardiac implantable electronic devices.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-19 DOI:10.1515/jom-2023-0218

Jacqueline Nikakis, Ermin Tale, Denis Malkov, Uddampreet S Arora, Jordan Keys, To Shan Li, Sheldon C Yao, Todd J Cohen

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Abstract

CONTEXT Osteopathic manipulative treatment (OMT) has been demonstrated to have an effect on the autonomic nervous system, which may have antiarrhythmic effects. The effects of OMT in patients with cardiac implantable electronic devices (CIEDs) have not previously been reported. This study investigated the impact of OMT on quality of life (QOL) in this patient population. OBJECTIVES The purpose of this study is to investigate the effects of OMT on QOL in CIED patients. METHODS Subjects with CIEDs were recruited into a double-blind randomized controlled institutional review board (IRB)-approved clinical trial (ClinicalTrials.gov ID: NCT04004741) and randomized to OMT or light touch (control) groups. Subjects received a one-time intervention, performed by board-certified neuromusculoskeletal medicine (NMM) and osteopathic manipulative medicine (OMM) physicians. The OMT protocol utilized techniques including myofascial release, rib raising, facilitated positional release (FPR), and osteopathic cranial manipulative medicine. Subjects' QOL was assessed immediately preceding intervention and one-month postintervention utilizing the Research ANd Development (RAND) 36-Item Short Form Health Survey (SF-36, eight parameters). Groups were compared utilizing unpaired t tests; α=0.05. RESULTS Forty-two subjects were enrolled, with four lost to follow-up, which resulted in 19 OMT and 19 control subjects for analysis. Of the eight QOL parameters, two showed significant improvement with OMT: role limitations due to physical health (p=0.001) and pain (p=0.003). CONCLUSIONS This study demonstrates the potential for QOL improvement in CIED patients. Specifically, subjects in the OMT group reported an improvement in activities of daily living as well as a decrease in overall pain, including pain interfering with work. Additional research is necessary to further understand the physiologic effects of OMT, including its effects on arrhythmias, in CIED patients.

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整骨疗法对心脏植入式电子装置患者生活质量的影响。

CONTEXTOsteopathic manipulative treatment（OMT）已被证实对自律神经系统有影响，可能具有抗心律失常的作用。关于整骨疗法对心脏植入式电子装置（CIED）患者的影响，此前尚未见报道。本研究旨在调查 OMT 对 CIED 患者生活质量（QOL）的影响。方法将 CIED 受试者招募到机构审查委员会（IRB）批准的双盲随机对照临床试验（ClinicalTrials.gov ID：NCT04004741）中，并随机分配到 OMT 组或轻触组（对照组）。受试者接受一次性干预，由获得神经肌肉骨骼医学（NMM）和整骨疗法（OMM）认证的医生实施。整骨疗法方案采用的技术包括肌筋膜松解术、肋骨抬高术、体位促进松解术（FPR）和颅骨整骨疗法。受试者的 QOL 在干预前和干预后一个月进行评估，采用研究与发展（RAND）36 项简表健康调查（SF-36，8 个参数）。结果共有 42 名受试者参加，其中 4 人失去了随访机会，因此分析对象为 19 名 OMT 受试者和 19 名对照组受试者。在八项QOL参数中，有两项参数在OMT治疗后有明显改善：身体健康导致的角色限制（p=0.001）和疼痛（p=0.003）。具体而言，OMT组的受试者报告日常生活活动有所改善，总体疼痛有所减轻，包括影响工作的疼痛。要进一步了解 OMT 对 CIED 患者的生理影响，包括对心律失常的影响，还需要进行更多的研究。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.