Bamboozled by Bonferroni

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-22 DOI:10.1017/psa.2024.13

Conor Mayo-Wilson

引用次数: 0

Abstract

When many statistical hypotheses are evaluated simultaneously, statisticians often recommend adjusting (or correcting) standard hypothesis tests. In this paper, I (1) distinguish two senses of adjustment, (2) investigate the prudential and epistemic goals that adjustment might achieve, and (3) identify conditions under which a researcher should not adjust for multiplicity in the two senses I identify. I tentatively conclude that the goals of scientists and the public may be misaligned with the decision criteria used to evaluate multiple testing regimes.

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被邦弗罗尼迷惑

当同时评估多个统计假设时，统计学家通常会建议调整（或修正）标准假设检验。在本文中，我（1）区分了两种意义上的调整，（2）研究了调整可能实现的审慎目标和认识论目标，（3）确定了在哪些条件下研究人员不应按照我所确定的两种意义对多重性进行调整。我的初步结论是，科学家和公众的目标可能与用于评估多重检验制度的决策标准不一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.