Comparative evaluation of the efficacy of probiotic, Aloe vera, povidine-iodine, and chlorhexidine mouthwashes in the treatment of gingival inflammation: A randomized controlled trial.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-04-23 DOI:10.17219/dmp/156425

R. Boyapati, Jyothirmayee Peeta, Ravindranath Dhulipalla, Lakshmikanth Kolaparthy, Chaitanya Adurty, Ramya Naga Shivani Cheruvu

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Abstract

BACKGROUND Chemical plaque control with mouthwashes as an adjunct to mechanical plaque control with a toothbrush and dental floss has been considered an effective method for controlling gingivitis. The anti-inflammatory effects of chemical plaque control benefit the oral tissues by reducing inflammation and bleeding. OBJECTIVES The aim of the present study was to evaluate and compare the clinical efficacy of probiotic, Aloe vera, povidine-iodine, and chlorhexidine (CHX) mouthwashes in treating gingivitis patients by assessing changes in their clinical parameters. MATERIAL AND METHODS This prospective study was conducted on 40 patients from our outpatient department, divided into 4 groups of 10 patients each: probiotic mouthwash group (group 1); herbal (Aloe vera) mouthwash group (group 2); povidone-iodine mouthwash group (group 3); and CHX mouthwash group (group 4). All participants were provided with the same type of manual toothbrush, the Pepsodent® toothpaste and a respective mouthwash for twice-daily use until the end of a 28-day observation period. Clinical parameters, such as the marginal plaque index (MPI) and bleeding on interdental brushing (BOIB), were recorded at baseline, and on the 14th and 28th day of the study period. RESULTS All groups showed a significant decrease in the MPI and BOIB scores. The results were similar in patients who used a probiotic mouthwash and those who used a CHX mouthwash. A comparable change in the mean scores was observed among the herbal and povidone-iodine groups from baseline to day 28. CONCLUSIONS In the treatment of chronic gingivitis patients,a probiotic mouthwash was nearly as effective as CHX in reducing the plaque and bleeding scores. It showed better results in all clinical parameters than herbal and povidone-iodine mouthwashes. Using a mouthwash along with routine tooth brushing can help in treating gingivitis and slow the progression of the periodontal disease.

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益生菌、芦荟、洗必泰-碘和洗必泰漱口水治疗牙龈炎症疗效的比较评估：随机对照试验。

背景用漱口水进行化学菌斑控制，作为用牙刷和牙线进行机械菌斑控制的辅助方法，一直被认为是控制牙龈炎的有效方法。本研究旨在通过评估牙龈炎患者临床参数的变化，评估和比较益生菌、芦荟、聚维丁碘和洗必泰（CHX）漱口水在治疗牙龈炎患者方面的临床疗效。材料和方法这项前瞻性研究的对象是本院门诊部的 40 名患者，分为 4 组，每组 10 人：益生菌漱口水组（第 1 组）、草本（芦荟）漱口水组（第 2 组）、聚维酮碘漱口水组（第 3 组）和 CHX 漱口水组（第 4 组）。所有参与者均使用同一种手动牙刷、百事可乐®牙膏和相应的漱口水，每天使用两次，直至 28 天观察期结束。临床参数，如边缘牙菌斑指数（MPI）和刷牙时牙间隙出血量（BOIB），在基线、研究期的第 14 天和第 28 天均有记录。使用益生菌漱口水和使用 CHX 漱口水的患者的结果相似。结论在治疗慢性牙龈炎患者时，益生菌漱口水在降低牙菌斑和出血评分方面的效果几乎与 CHX 相同。在所有临床参数方面，益生菌漱口水的效果都优于草药漱口水和聚维酮碘漱口水。在日常刷牙的同时使用漱口水有助于治疗牙龈炎和减缓牙周病的发展。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.