Successful treatment of eosinophilia associated with dialysis-related renal cancer with radical nephrectomy

Q4 Medicine

IJU Case Reports Pub Date : 2024-04-24 DOI:10.1002/iju5.12729

Yuta Goto M.D., Daichi Tamura, Tomohiko Matsuura, Ei Shiomi, Daiki Ikarashi, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Wataru Obara

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Abstract

Introduction

Secondary eosinophilia due to solid tumors is a rare case. This is the first study to report secondary eosinophilia due to renal cancer in a patient on dialysis.

Case presentation

A 70-year-old man, on long-term hemodialysis was incidentally detected with right renal cancer, and workup performed revealed eosinophilia. Allergic symptoms caused by hemodialysis were initially considered; however, treatment did not lead to any improvement in eosinophilia. Therefore, nephrectomy for renal cancer was performed. The resolution of symptoms and eosinophilia after surgery suggested renal cancer as the cause of eosinophilia.

Conclusion

As demonstrated in this patient with dialysis-related renal cancer, eosinophilia associated with solid tumors may be addressed by treating the tumor.

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用根治性肾切除术成功治疗与透析相关的肾癌伴发的嗜酸性粒细胞增多症

实体瘤引起的继发性嗜酸性粒细胞增多症是一种罕见病例。这是首例报告透析患者因肾癌导致继发性嗜酸性粒细胞增多症的研究。一名 70 岁的男性患者长期接受血液透析，偶然被查出患有右肾癌，检查发现患有嗜酸性粒细胞增多症。最初考虑是血液透析引起的过敏症状，但治疗并没有改善嗜酸性粒细胞增多症。因此，该患者接受了肾癌肾切除术。手术后症状和嗜酸性粒细胞增多症均得到缓解，这表明肾癌是导致嗜酸性粒细胞增多症的原因。

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