The Impact of Mammographic, Radiologist, and Patient Factors on the Likelihood of Probably Benign (BI-RADS 3) Assessment at Diagnostic Mammography.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-04-24 DOI:10.1093/jbi/wbae014

Allyson L Chesebro, Nooshin Abbasi, Ronilda C. Lacson, S. Chikarmane, Andro Licaros, C. Giess

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引用次数: 0

Abstract

OBJECTIVE To evaluate the association of mammographic, radiologist, and patient factors on BI-RADS 3 assessment at diagnostic mammography in patients recalled from screening mammography. METHODS This Institutional Review Board-approved retrospective study of consecutive unique diagnostic mammography examinations in asymptomatic patients recalled from screening mammography March 5, 2014, to December 31, 2019, was conducted in a single large United States health care institution. Mammographic features (mass, calcification, distortion, asymmetry), breast density, prior examination, and BI-RADS assessment were extracted from reports by natural language processing. Patient age, race, and ethnicity were extracted from the electronic health record. Radiologist years in practice, recall rate, and number of interpreted diagnostic mammograms were calculated. A mixed effect logistic regression model evaluated factors associated with likelihood of BI-RADS 3 compared with other BI-RADS assessments. RESULTS A total of 12 080 diagnostic mammography examinations were performed during the study period, yielding 2010 (16.6%) BI-RADS 3 and 10 070 (83.4%) other BI-RADS assessments. Asymmetry (odds ratio [OR] = 6.49, P <.001) and calcification (OR = 5.59, P <.001) were associated with increased likelihood of BI-RADS 3 assessment; distortion (OR = 0.20, P <.001), dense breast parenchyma (OR = 0.82, P <.001), prior examination (OR = 0.63, P = .01), and increasing patient age (OR = 0.99, P <.001) were associated with decreased likelihood. Mass, patient race or ethnicity, and radiologist factors were not significantly associated with BI-RADS 3 assessment. Malignancy rate for BI-RADS 3 lesions was 1.6%. CONCLUSION Asymmetry and calcifications had an increased likelihood of BI-RADS 3 assessment at diagnostic evaluation with low likelihood of malignancy, while radiologist features had no association.

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乳腺 X 线造影术、放射医师和患者因素对诊断性乳腺 X 线造影术中良性（BI-RADS 3）评估可能性的影响。

目的评估乳腺X线摄影、放射医师和患者因素与乳腺X线摄影筛查召回患者诊断性乳腺X线摄影的BI-RADS 3评估之间的关联。方法在美国一家大型医疗机构对2014年3月5日至2019年12月31日期间乳腺X线摄影筛查召回的无症状患者的连续独特诊断性乳腺X线摄影检查进行了机构审查委员会批准的回顾性研究。通过自然语言处理从报告中提取了乳腺X光特征（肿块、钙化、变形、不对称）、乳腺密度、之前的检查和BI-RADS评估。患者的年龄、种族和民族是从电子健康记录中提取的。计算了放射科医生的执业年限、召回率和诊断性乳房 X 线照片的解释次数。混合效应逻辑回归模型评估了 BI-RADS 3 与其他 BI-RADS 评估的相关因素。结果在研究期间共进行了 12 080 次诊断性乳腺 X 光检查，其中 2010 次（16.6%）为 BI-RADS 3，10 070 次（83.4%）为其他 BI-RADS 评估。不对称（几率比 [OR] = 6.49，P <.001）和钙化（OR = 5.59，P <.001）与 BI-RADS 3 评估的可能性增加有关；扭曲（OR = 0.20，P <.001）、致密乳腺实质（OR = 0.82，P <.001）、先前检查（OR = 0.63，P = .01）和患者年龄增加（OR = 0.99，P <.001）与可能性降低有关。质量、患者种族或民族以及放射医师因素与 BI-RADS 3 评估无明显关联。结论诊断评估时，不对称和钙化增加了 BI-RADS 3 评估的可能性，但恶性的可能性较低，而放射医师的特征与之无关。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.