Revisiting the Use of Deep Temporalis Fascia Grafts in Ophthalmology.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
E. Razlog, Alexandre Denoyer, Stéphanie Baillif, Carl Arndt, Xavier Dubernard, J. Caujolle, S. Nahon-Estève, Arnaud Martel
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Abstract

PURPOSE To report new indications for deep temporalis fascia (DTF) grafts in the ophthalmic field. METHODS Monocentric retrospective interventional case series study. All the patients who underwent a DTF graft in an unpublished new indication over the study period (May 2020-October 2023) were included. For each patient, gender, age, graft indication, outcomes, complications, and follow-up duration were collected. In most cases, the DTF graft was covered by a vascularized flap. RESULTS Eight patients underwent a DTF graft over the study period. The indications were: radiotherapy-induced scleral necrosis in three cases, tendinoplasty to replace the inferior rectus muscle tendon invaded by a locally advanced conjunctival carcinoma in one case, Ahmed glaucoma valve tube exposure in one case, intraocular lens with scleral fixation exposure in one case, orbital cerebrospinal fluid fistula (orbitorrhea) in one case, and post-traumatic complete corneal graft loss in one case. The DTF graft was successful in 87.5% of cases after a mean follow-up of 11.4 months. No complications were observed. CONCLUSIONS DTF graft is a highly versatile graft that can be easily harvested. New indications for DTF grafts may include the repair of radiotherapy-induced scleral necrosis, the creation of oculomotor tendon and the temporary packing of large ocular tissue loss in an emergency context. Further studies with a longer follow-up are needed to confirm our preliminary results.
重新审视深颞筋膜移植在眼科中的应用。
目的报告眼科领域深颞筋膜(DTF)移植的新适应症。方法单中心回顾性介入病例系列研究。纳入所有在研究期间(2020 年 5 月至 2023 年 10 月)接受未公开新适应症 DTF 移植的患者。研究人员收集了每位患者的性别、年龄、移植适应症、结果、并发症和随访时间。在大多数情况下,DTF移植物由血管化皮瓣覆盖。研究期间共有8名患者接受了DTF移植手术,其适应症包括:3例放疗引起的巩膜坏死;1例为替代被局部晚期结膜癌侵袭的下直肌肌腱而进行的肌腱成形术;1例Ahmed青光眼瓣管暴露;1例眼球内晶状体与巩膜固定暴露;1例眶脑脊液瘘(orbitorrhea);1例外伤后完全角膜移植缺失。平均随访 11.4 个月后,87.5% 的病例成功进行了 DTF 移植。结论DTF移植物是一种用途广泛、易于采集的移植物。DTF移植物的新适应症可能包括修复放疗引起的巩膜坏死、创建眼球运动肌腱以及在紧急情况下对大量眼组织缺失进行临时包装。要证实我们的初步结果,还需要进行更长时间的随访研究。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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