Micro-needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

IF 3.4 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of periodontal research Pub Date : 2024-04-25 DOI:10.1111/jre.13271

Salma Zaaya, Weam Elbattawy, Sarah Yusri, Karim M. Fawzy El-Sayed

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引用次数: 0

Abstract

Aims

This randomized trial assessed for the first time the efficacy of coronally advanced flap (CAF) followed by micro-needling (MN) in contrast to CAF with acellular dermal matrix (ADM) on gingival thickness (GT, primary outcome), keratinized tissue width (KTW), clinical attachment level (CAL), probing depth (PD), recession depth (RD), recession width (RW), recession reduction (Rec-Red), complete root coverage (CRC) and percentage of root coverage (all secondary outcomes) in management of RT1 gingival recession in patients with thin gingival phenotype.

Methods

A total of 24 patients (n = 24) with a thin gingival phenotype and single RT1 gingival recession in the aesthetic zone were randomly allocated to test- (CAF + MN; n = 12) or control group (CAF + ADM; n = 12). All clinical parameters were evaluated at baseline, 3 and 6 months.

Results

Both groups independently demonstrated significant gain in GT, RW, RD, CAL, PD, Rec-Red, CRC and percentage of root coverage, with reduced PI and BOP (p < .05) at 3 and 6 months, without intergroup differences (p > .05). At 6 months, KTW gain was significantly higher in CAF + MN (5.08 ± 0.9 mm) than in CAF + ADM-group (4.25 ± 1.06 mm; p < .05). Stepwise linear regression model with GT as dependent variable showed that base-line GT was the only statistically significant predictor for GT with a direct correlation between base-line GT and GT after 6 months.

Conclusion

CAF followed by MN could represent a promising graft-less approach for increasing gingival thickness, comparable to CAF with ADM, with superior keratinized tissue width improvement, in the treatment of RT1 recession defects in patients with thin gingival phenotype.

Abstract Image

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微针疗法与细胞真皮基质在 RT1 牙龈退缩覆盖中的对比：随机临床试验。

目的这项随机试验首次评估了冠状先进皮瓣（CAF）后微针（MN）与带有细胞真皮基质（ADM）的CAF在牙龈厚度（GT，主要结果）、角化组织宽度（KTW）、临床附着水平（CAL）、探头深度（PD）、退缩深度（RD）、退缩宽度（RW）、退缩减少（Rec-Red）、完全根覆盖（CRC）和根覆盖率（所有次要结果）方面的疗效、探诊深度 (PD)、退缩深度 (RD)、退缩宽度 (RW)、退缩缩小 (Rec-Red)、完全根覆盖 (CRC) 和根覆盖百分比（所有次要结果）的影响。方法将 24 名牙龈薄且在美学区有单个 RT1 牙龈退缩的患者（n = 24）随机分配到试验组（CAF + MN；n = 12）或对照组（CAF + ADM；n = 12）。结果两组的 GT、RW、RD、CAL、PD、Rec-Red、CRC 和牙根覆盖率均有显著提高，PI 和 BOP 有所降低（P .05）。6 个月时，CAF + MN 组的 KTW 增量（5.08 ± 0.9 mm）明显高于 CAF + ADM 组（4.25 ± 1.06 mm；P < .05）。以GT为因变量的逐步线性回归模型显示，基线GT是预测GT的唯一具有统计学意义的因素，基线GT与6个月后的GT之间存在直接相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of periodontal research 医学-牙科与口腔外科

CiteScore

6.90

自引率

5.70%

发文量

103

审稿时长

6-12 weeks

期刊介绍： The Journal of Periodontal Research is an international research periodical the purpose of which is to publish original clinical and basic investigations and review articles concerned with every aspect of periodontology and related sciences. Brief communications (1-3 journal pages) are also accepted and a special effort is made to ensure their rapid publication. Reports of scientific meetings in periodontology and related fields are also published. One volume of six issues is published annually.