Impact of acquisition volume on cone beam computed tomography imaging of marginal bone: an ex vivo study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-25 DOI:10.2340/aos.v83.40494

M. Ruetters, Korallia Alexandrou, H. Gehrig, Sinclair Awounvo, Ti-Sun Kim, Anna Felten, Christopher Lux, Sinan Sen

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Abstract

OBJECTIVE The current study explores whether there is a clinically relevant distinction in the measurement of marginal bone loss when comparing high-dose (HD) versus low-dose (LD) cone beam computed tomography (CBCT) protocols in small and large acquisition volumes. Material and Methods: CBCTs of four human cadaveric preparates were taken in HD and LD mode in two different fields of view 8 × 8 cm2 (LV) and 5 × 5 cm2 (SV). In total, 43 sites of 15 teeth were randomly chosen, and marginal bone loss was measured twice in all protocols at 43 sites of 15 teeth by one calibrated investigator. Bland-Altman plots and Lin's concordance correlation coefficient (CCC) were calculated to assess the extent of agreement of the measurements. Additionally, the rater scored the certainty in each of the measurements. RESULTS For HD-CBCT CCC of measurements obtained using SV versus LV was 0.991. CCC of measurements obtained using SV versus LV of LD-CBCT was 0.963. Both CCC values indicated excellent agreement between the two volumes in both protocols. CCC also indicated high intramodality correlation between HD-CBCT and LD-CBCT independent of the acquisition volume (0.963 - 0.992). Bland-Altman plots also indicated no substantial differences. Results of certainty scoring showed significant differences (p = 0.004 (LV), p < 0.001(SV)) between the LD and HD-CBCT. CONCLUSIONS Accuracy of measurements of bone loss shows no clinical noticeable effects depending on the CBCT volume in this ex vivo study. There appears to be no relevant advantage of SV over LV, neither in HD-CBCT nor in LD-CBCT and additionally no relevant advantage of HD versus LD in visualizing marginal bone loss.

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采集体积对边缘骨锥束计算机断层扫描成像的影响：一项体外研究。

目的：本研究探讨了在比较高剂量（HD）和低剂量（LD）锥束计算机断层扫描（CBCT）方案在小采集量和大采集量时，边缘骨质流失的测量是否存在临床相关性差异。材料和方法：在 8 × 8 平方厘米（LV）和 5 × 5 平方厘米（SV）两种不同视野下，以 HD 和 LD 模式对四具人体尸体制备体进行 CBCT 扫描。共随机选择了 15 颗牙齿的 43 个部位，由一名经过校准的研究人员在所有方案中对 15 颗牙齿的 43 个部位的边缘骨质流失进行了两次测量。通过计算Bland-Altman图和Lin's concordance相关系数（CCC）来评估测量结果的一致程度。结果对于 HD-CBCT，使用 SV 与 LV 测量的 CCC 为 0.991。LD-CBCT 使用 SV 与 LV 测量的 CCC 值为 0.963。这两个 CCC 值表明两种方案中两个容积之间的一致性非常好。 CCC 还表明，HD-CBCT 和 LD-CBCT 的模内相关性很高，与采集容积无关（0.963 - 0.992）。Bland-Altman 图也显示两者没有实质性差异。确定性评分结果显示 LD 和 HD-CBCT 之间存在显著差异（p = 0.004 (LV)，p < 0.001(SV)）。无论是在 HD-CBCT 还是在 LD-CBCT 中，SV 与 LV 相比似乎都没有相关优势，此外，在观察边缘骨质流失方面，HD 与 LD 相比也没有相关优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.