Pharmacogenomic-guided treatment slightly improves antidepressant efficacy

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Abstract

A systematic review and meta-analysis encompassing 15 clinical trials has concluded that pharmaco­genomic-guided depression treatment results in a small improvement in antidepressant efficacy relative to treatment as usual. There was no difference in treatment discontinuation rates between pharmaco­genomic-guided and conventional treatment.

药物基因组学指导治疗略微提高了抗抑郁疗效
一项包含15项临床试验的系统性回顾和荟萃分析得出结论,药物基因组学指导下的抑郁症治疗与常规治疗相比,抗抑郁疗效略有提高。药物基因组指导治疗与常规治疗在治疗中断率方面没有差异。
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