Assessing feasibility of conducting medication review with follow-up among older adults at community pharmacy: a pilot randomised controlled trial

IF 2.6 4区医学 Q2 PHARMACOLOGY & PHARMACY

International Journal of Clinical Pharmacy Pub Date : 2024-04-18 DOI:10.1007/s11096-024-01711-3

Christina Malini Christopher, Ali Qais Blebil, KC Bhuvan, Deepa Alex, Mohamed Izham Mohamed Ibrahim, Norhasimah Ismail, Mark Wing Loong Cheong

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Abstract

Background

Medication review with follow-up is essential for optimising medication utilisation among the older adult population in primary healthcare.

Aim

This study aimed to evaluate the feasibility of implementing medication reviews with follow-up for older adults in community pharmacies and examined potential outcomes on medication use.

Method

A pilot randomised controlled trial was conducted with 4 cluster-randomised community pharmacies to assess the feasibility of the intervention. Two community pharmacies served as intervention and control groups. Both groups recruited older adults over 60 who were followed over 6 months. The translated Medication use Questionnaire (MedUseQ) was administered at baseline and 6 months for both groups. The outcomes were to assess the feasibility of conducting medication review with follow-up and the probable medication use outcomes from the intervention.

Results

The intervention and control groups comprised 14 and 13 older adults. A total of 35 recommendations were made by pharmacists in the intervention group and 8 in the control group. MedUseQ was easily administered, providing some evidence the feasibility of the intervention. However, there were feasibility challenges such as a lack of pharmacists, collaborative practice, difficulties with the tool language, time constraints, and limited funds. Questionnaire results provided a signal of improvement in medication administration, adherence, and polypharmacy among intervention participants. The incidence of drug related problems was significantly higher in the control group (median = 1) after 6 months, U = 15, z = − 2.98, p = 0.01.

Conclusion

Medication review with follow-up is potentialy practical in community pharmacies, but there are feasibility issues. While these challenges can be addressed, it is essential to study larger sample sizes to establish more robust evidence regarding outcomes.

Clinical trial registry: ClinicalTrials.Gov NCT05297461.

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评估在社区药房对老年人进行药物随访的可行性：随机对照试验

本研究旨在评估在社区药房对老年人实施随访式用药回顾的可行性，并研究其对用药的潜在影响。方法在 4 家分组随机对照的社区药房开展了一项试点随机对照试验，以评估干预措施的可行性。两家社区药房分别作为干预组和对照组。两组均招募了 60 岁以上的老年人，对他们进行了为期 6 个月的跟踪调查。两组均在基线和 6 个月内进行了药物使用情况调查问卷（MedUseQ）的翻译。结果干预组和对照组分别有 14 名和 13 名老年人。干预组药剂师共提出 35 条建议，对照组药剂师提出 8 条建议。MedUseQ 易于实施，这在一定程度上证明了干预的可行性。然而，在可行性方面也存在一些挑战，如缺乏药剂师、合作实践、工具语言方面的困难、时间限制和资金有限等。问卷调查结果显示，干预参与者在用药、依从性和多种药物治疗方面都有所改善。6 个月后，对照组的药物相关问题发生率（中位数 = 1）明显高于干预组，U = 15, z = - 2.98, p = 0.01。虽然这些问题可以解决，但必须进行更大规模的样本研究，以建立更可靠的结果证据：临床试验登记：ClinicalTrials.Gov NCT05297461。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Clinical Pharmacy PHARMACOLOGY & PHARMACY-

CiteScore

4.10

自引率

8.30%

发文量

131

审稿时长

4-8 weeks

期刊介绍： The International Journal of Clinical Pharmacy (IJCP) offers a platform for articles on research in Clinical Pharmacy, Pharmaceutical Care and related practice-oriented subjects in the pharmaceutical sciences. IJCP is a bi-monthly, international, peer-reviewed journal that publishes original research data, new ideas and discussions on pharmacotherapy and outcome research, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics, the clinical use of medicines, medical devices and laboratory tests, information on medicines and medical devices information, pharmacy services research, medication management, other clinical aspects of pharmacy. IJCP publishes original Research articles, Review articles , Short research reports, Commentaries, book reviews, and Letters to the Editor. International Journal of Clinical Pharmacy is affiliated with the European Society of Clinical Pharmacy (ESCP). ESCP promotes practice and research in Clinical Pharmacy, especially in Europe. The general aim of the society is to advance education, practice and research in Clinical Pharmacy . Until 2010 the journal was called Pharmacy World & Science.