Comparative Efficacy of Dopamine Partial Agonists by Doses for Treatment-Resistant Depression: A Systematic Review and Dose-Response Model-Based Network Meta-analysis.

IF 2.9 3区医学 Q2 PHARMACOLOGY & PHARMACY

Journal of Clinical Psychopharmacology Pub Date : 2024-04-19 DOI:10.1097/jcp.0000000000001862

Itsuki Terao, Wakako Kodama

引用次数: 0

Abstract

The augmentative antidepressant effects of dopamine partial agonists (aripiprazole, brexpiprazole, and cariprazine) for treatment-resistant depression have been compared in a previous network meta-analysis. However, the comparative efficacy of the dose-responses of these drugs remains unclear. Therefore, we aimed to estimate the dose-response relationships and compare the effects of each dopamine partial agonist doses.

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多巴胺部分激动剂治疗难治性抑郁症的剂量疗效比较：多巴胺部分激动剂治疗难治性抑郁症的剂量疗效比较：系统综述和基于剂量反应模型的网络 Meta 分析》。

先前的一项网络荟萃分析比较了多巴胺部分激动剂（阿立哌唑、布瑞哌唑和卡哌嗪）对治疗耐药抑郁症的增强抗抑郁作用。然而，这些药物的剂量反应的疗效比较仍不清楚。因此，我们旨在估算剂量-反应关系，并比较每种多巴胺部分激动剂剂量的效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Psychopharmacology 医学-精神病学

CiteScore

4.00

自引率

3.40%

发文量

231

审稿时长

4-8 weeks

期刊介绍： Journal of Clinical Psychopharmacology, a leading publication in psychopharmacology, offers a wide range of articles reporting on clinical trials and studies, side effects, drug interactions, overdose management, pharmacogenetics, pharmacokinetics, and psychiatric effects of non-psychiatric drugs. The journal keeps clinician-scientists and trainees up-to-date on the latest clinical developments in psychopharmacologic agents, presenting the extensive coverage needed to keep up with every development in this fast-growing field.