Taming glycosylidene carbenes through bench-stable glycosylidene diaziridines to access boro-ketosides

Abstract

In this issue of Chem Catalysis, He and co-workers demonstrate easy access to diverse glycosyl boro-ketosides via a rare glycosylidene carbene intermediate. They use stable glycosylidene diaziridines as precursors for carbene generation, leading to products convertible into rare sugars and pharmaceutically interesting derivatives, such as tofogliflozin.