Remote enantioselective desymmetrization of cyclohexanone with carbonyl 1,2-transposition

IF 11.5 Q1 CHEMISTRY, PHYSICAL

Chem Catalysis Pub Date : 2024-04-18 DOI:10.1016/j.checat.2024.100974

Hong Lu, Hao Wei

引用次数: 0

Abstract

In this issue of Chem Catalysis, Ye and co-workers present a bisguanidinium-catalyzed method involving an intramolecular carbonyl 1,2-transposition for the remote enantioselective desymmetrization of prochiral cyclohexanone. The comprehensive mechanistic experiments, coupled with density functional theory (DFT) calculations, lay a robust foundation for future advancements in functional-group transposition.

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环己酮与羰基 1,2-反式的远程对映选择性非对称转化

在本期的《化学催化》（Chem Catalysis）杂志上，Ye 及其合作者介绍了一种双胍催化方法，该方法涉及分子内羰基 1,2 转位，用于亲手性环己酮的远程对映选择性去对称化。全面的机理实验与密度泛函理论（DFT）计算相结合，为官能团转位的未来发展奠定了坚实的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chem Catalysis

CiteScore

10.50

自引率

6.40%

发文量

期刊介绍： Chem Catalysis is a monthly journal that publishes innovative research on fundamental and applied catalysis, providing a platform for researchers across chemistry, chemical engineering, and related fields. It serves as a premier resource for scientists and engineers in academia and industry, covering heterogeneous, homogeneous, and biocatalysis. Emphasizing transformative methods and technologies, the journal aims to advance understanding, introduce novel catalysts, and connect fundamental insights to real-world applications for societal benefit.