Prevalence of crimean Congo hemorrhagic fever in Khyber Pakhtunkhwa, Pakistan

IF 6.3 3区医学 Q1 INFECTIOUS DISEASES

Travel Medicine and Infectious Disease Pub Date : 2024-04-18 DOI:10.1016/j.tmaid.2024.102722

Asad Zia , Ali Talha Khalil , Naz Alam , Abdul Qadoos Khan , Mubarak Ali Khan , Yasar Yosafzai , Asif Ali , Ihsan Ullah , Ali Rehman Wazir

{"title":"Prevalence of crimean Congo hemorrhagic fever in Khyber Pakhtunkhwa, Pakistan","authors":"Asad Zia , Ali Talha Khalil , Naz Alam , Abdul Qadoos Khan , Mubarak Ali Khan , Yasar Yosafzai , Asif Ali , Ihsan Ullah , Ali Rehman Wazir","doi":"10.1016/j.tmaid.2024.102722","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>CCHFV is well recognized as a major public health threat and its prevalence and epidemiological distribution in Pakistan and specifically in KP province is not well documented.</p></div><div><h3>Methods</h3><p>We used a gold-standard PCR-based diagnostic assay for confirmation of CCHFV among suspected patients. A total of 150 patients were enrolled from June 2022 to September 2022 and their blood samples were collected for PCR confirmation.</p></div><div><h3>Results</h3><p>The overall positivity rate for CCHFV was 26.67 %, with the virus mostly prevalent in the middle-aged group (21–40 years). In the July of 2022, a significant spike in the prevalence of CCHFV was observed in provincial capital Peshawar with the highest burden (31.57 %).</p></div><div><h3>Conclusion</h3><p>Our findings indicate the necessity of strengthening CCHFV monitoring programs and intensifying efforts to identify hotspot regions for effective surveillance and control of CCHFV. The months before the Eid-ul-Adha are crucial in the context of CCHFV control.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102722"},"PeriodicalIF":6.3000,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S147789392400036X/pdfft?md5=a579dde5635a4b4c9e163773ff9aed68&pid=1-s2.0-S147789392400036X-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Travel Medicine and Infectious Disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S147789392400036X","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

CCHFV is well recognized as a major public health threat and its prevalence and epidemiological distribution in Pakistan and specifically in KP province is not well documented.

Methods

We used a gold-standard PCR-based diagnostic assay for confirmation of CCHFV among suspected patients. A total of 150 patients were enrolled from June 2022 to September 2022 and their blood samples were collected for PCR confirmation.

Results

The overall positivity rate for CCHFV was 26.67 %, with the virus mostly prevalent in the middle-aged group (21–40 years). In the July of 2022, a significant spike in the prevalence of CCHFV was observed in provincial capital Peshawar with the highest burden (31.57 %).

Conclusion

Our findings indicate the necessity of strengthening CCHFV monitoring programs and intensifying efforts to identify hotspot regions for effective surveillance and control of CCHFV. The months before the Eid-ul-Adha are crucial in the context of CCHFV control.

查看原文本刊更多论文

巴基斯坦开伯尔巴图克瓦省的刚果出血热流行情况

背景CCHFV被公认为是一种重大的公共卫生威胁，但其在巴基斯坦，特别是在KP省的流行率和流行病学分布却没有得到很好的记录。结果CCHFV的总体阳性率为26.67%，病毒主要流行于中年群体（21-40岁）。结论我们的研究结果表明，有必要加强 CCHFV 监测项目，并加大力度确定热点地区，以有效监测和控制 CCHFV。宰牲节前的几个月是控制 CCHFV 的关键时期。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

19.40

自引率

1.70%

发文量

211

审稿时长

49 days

期刊介绍： Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers