Wende Dong , Chenlong Zhu , Dan Xie , Yanli Zhang , Shuyin Tao , Chao Tian
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引用次数: 0
Abstract
Ring-array photoacoustic tomography (PAT) system has been widely used in noninvasive biomedical imaging. However, the reconstructed image usually suffers from spatially rotational blur and streak artifacts due to the non-ideal imaging conditions. To improve the reconstructed image towards higher quality, we propose a concept of spatially rotational convolution to formulate the image blur process, then we build a regularized restoration problem model accordingly and design an alternating minimization algorithm which is called blind spatially rotational deconvolution to achieve the restored image. Besides, we also present an image preprocessing method based on the proposed algorithm to remove the streak artifacts. We take experiments on phantoms and in vivo biological tissues for evaluation, the results show that our approach can significantly enhance the resolution of the image obtained from ring-array PAT system and remove the streak artifacts effectively.
环形阵光声断层成像(PAT)系统已广泛应用于无创生物医学成像。然而,由于成像条件不理想,重建图像通常会出现空间旋转模糊和条纹伪影。为了提高重建图像的质量,我们提出了空间旋转卷积的概念来表述图像模糊过程,并据此建立了正则化还原问题模型,设计了一种交替最小化算法,即盲空间旋转解卷积算法来实现还原图像。此外,我们还提出了一种基于所提算法的图像预处理方法,以去除条纹伪影。我们在模型和活体生物组织上进行了实验评估,结果表明我们的方法可以显著提高环阵 PAT 系统获得的图像的分辨率,并有效去除条纹伪影。
PhotoacousticsPhysics and Astronomy-Atomic and Molecular Physics, and Optics
CiteScore
11.40
自引率
16.50%
发文量
96
审稿时长
53 days
期刊介绍:
The open access Photoacoustics journal (PACS) aims to publish original research and review contributions in the field of photoacoustics-optoacoustics-thermoacoustics. This field utilizes acoustical and ultrasonic phenomena excited by electromagnetic radiation for the detection, visualization, and characterization of various materials and biological tissues, including living organisms.
Recent advancements in laser technologies, ultrasound detection approaches, inverse theory, and fast reconstruction algorithms have greatly supported the rapid progress in this field. The unique contrast provided by molecular absorption in photoacoustic-optoacoustic-thermoacoustic methods has allowed for addressing unmet biological and medical needs such as pre-clinical research, clinical imaging of vasculature, tissue and disease physiology, drug efficacy, surgery guidance, and therapy monitoring.
Applications of this field encompass a wide range of medical imaging and sensing applications, including cancer, vascular diseases, brain neurophysiology, ophthalmology, and diabetes. Moreover, photoacoustics-optoacoustics-thermoacoustics is a multidisciplinary field, with contributions from chemistry and nanotechnology, where novel materials such as biodegradable nanoparticles, organic dyes, targeted agents, theranostic probes, and genetically expressed markers are being actively developed.
These advanced materials have significantly improved the signal-to-noise ratio and tissue contrast in photoacoustic methods.