{"title":"Utilization of Phytochemicals as Nutraceutical in the Prophylaxis of Dengue","authors":"Jyoti Baranwal, Swastika Singh, Smriti Kushwaha, Archana Jyoti","doi":"10.1007/s11094-024-03105-1","DOIUrl":null,"url":null,"abstract":"<p>Every year, during the monsoon season, dengue, an infectious disease transmitted by the <i>Aedes aegypti</i> mosquito and caused by the dengue virus, occurs. The frequency and prevalence of dengue fever, as well as deaths from its consequences, have increased dramatically in recent years. Despite the fact that the infection has affected a large number of people worldwide, no specific and efficient drug treatment is known. Researchers are working tirelessly to find a cure, focusing their efforts on developing therapeutic treatments that block or inhibit the activity of specific Dengue virus (DENV) proteins. This review focuses on the phytochemical constituents present in traditionally used natural remedies for the treatment of dengue such as papaya leaf extract, goat milk, kiwi fruit, dragon fruit, and coconut water. Undoubtedly, the contents of this review will motivate researchers to do more novel work in this area which will accelerate the journey towards the exploration of the pharmacological activity of natural compounds.</p>","PeriodicalId":19990,"journal":{"name":"Pharmaceutical Chemistry Journal","volume":"61 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutical Chemistry Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11094-024-03105-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Every year, during the monsoon season, dengue, an infectious disease transmitted by the Aedes aegypti mosquito and caused by the dengue virus, occurs. The frequency and prevalence of dengue fever, as well as deaths from its consequences, have increased dramatically in recent years. Despite the fact that the infection has affected a large number of people worldwide, no specific and efficient drug treatment is known. Researchers are working tirelessly to find a cure, focusing their efforts on developing therapeutic treatments that block or inhibit the activity of specific Dengue virus (DENV) proteins. This review focuses on the phytochemical constituents present in traditionally used natural remedies for the treatment of dengue such as papaya leaf extract, goat milk, kiwi fruit, dragon fruit, and coconut water. Undoubtedly, the contents of this review will motivate researchers to do more novel work in this area which will accelerate the journey towards the exploration of the pharmacological activity of natural compounds.
期刊介绍:
Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including:
methods of synthesis;
results of pharmacological, toxicological, and biochemical studies;
investigation of structure - activity relationships in prediction of new compounds;
methods and technical facilities used; and
problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April.
All articles are peer-reviewed.