Seroprevalence of visceral leishmaniasis among pregnant women in Jahrom city in Fars province, southern Iran

IF 2 Q3 INFECTIOUS DISEASES

Parasite Epidemiology and Control Pub Date : 2024-04-16 DOI:10.1016/j.parepi.2024.e00349

Najmeh Sadeghi , Mehdi Mohebali , Zahra Kakooei , Abazar Roustazadeh , Hamed Mir , Amir Abdoli , Kavous Solhjoo , Manoochehr Shabani , Enayatollah Shadmand , Ali Taghipour

{"title":"Seroprevalence of visceral leishmaniasis among pregnant women in Jahrom city in Fars province, southern Iran","authors":"Najmeh Sadeghi , Mehdi Mohebali , Zahra Kakooei , Abazar Roustazadeh , Hamed Mir , Amir Abdoli , Kavous Solhjoo , Manoochehr Shabani , Enayatollah Shadmand , Ali Taghipour","doi":"10.1016/j.parepi.2024.e00349","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Visceral leishmaniasis (VL) is a public health issue in endemic countries with poor sanitation facilities. In this study, the seroprevalence rate and associated risk factors of VL were investigated during September 2020 to February 2021 in pregnant women referred to Ostad Mottahari and Peymanieh hospitals in Jahrom county, Fars province, southern Iran.</p></div><div><h3>Material and methods</h3><p>A total of 220 serum samples of pregnant women were assessed for the presence of Anti<em>-Leishmania infantum</em> antibodies by direct agglutination antigen (DAT). The associated risk factors were obtained using questionnaires.</p></div><div><h3>Results</h3><p>The overall seroprevalence of VL in pregnant women was 12.72% (28/220). Considering the antibody titer, titer 1:1600 was detected in 23 samples, titer 1:3200 in 4 samples, and titer 1:6400 in one sample. All 5 women with titer >3200 had mild fever. As such, there was a statistically significant difference regarding the age (≥39 years old with <em>p-</em>value: 0.01).</p></div><div><h3>Conclusions</h3><p>We recommend an appropriate health education program for pregnant women and serological screening of VL before pregnancy in endemic cities. Moreover, we believed a need for more epidemiological studies for better understand the status of VL in pregnant women.</p></div>","PeriodicalId":37873,"journal":{"name":"Parasite Epidemiology and Control","volume":null,"pages":null},"PeriodicalIF":2.0000,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405673124000138/pdfft?md5=26783ad05c3c959373085e9475003755&pid=1-s2.0-S2405673124000138-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Parasite Epidemiology and Control","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405673124000138","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Visceral leishmaniasis (VL) is a public health issue in endemic countries with poor sanitation facilities. In this study, the seroprevalence rate and associated risk factors of VL were investigated during September 2020 to February 2021 in pregnant women referred to Ostad Mottahari and Peymanieh hospitals in Jahrom county, Fars province, southern Iran.

Material and methods

A total of 220 serum samples of pregnant women were assessed for the presence of Anti-Leishmania infantum antibodies by direct agglutination antigen (DAT). The associated risk factors were obtained using questionnaires.

Results

The overall seroprevalence of VL in pregnant women was 12.72% (28/220). Considering the antibody titer, titer 1:1600 was detected in 23 samples, titer 1:3200 in 4 samples, and titer 1:6400 in one sample. All 5 women with titer >3200 had mild fever. As such, there was a statistically significant difference regarding the age (≥39 years old with p-value: 0.01).

Conclusions

We recommend an appropriate health education program for pregnant women and serological screening of VL before pregnancy in endemic cities. Moreover, we believed a need for more epidemiological studies for better understand the status of VL in pregnant women.

查看原文本刊更多论文

伊朗南部法尔斯省贾赫罗姆市孕妇的内脏利什曼病血清流行率

背景皮损利什曼病（VL）是卫生设施落后的地方病流行国家的一个公共卫生问题。本研究调查了 2020 年 9 月至 2021 年 2 月期间在伊朗南部法尔斯省贾赫罗姆县 Ostad Mottahari 和 Peymanieh 医院转诊的孕妇中 VL 的血清流行率和相关风险因素。结果孕妇 VL 血清阳性率为 12.72%（28/220）。从抗体滴度来看，23 个样本的滴度为 1:1600，4 个样本的滴度为 1:3200，1 个样本的滴度为 1:6400。滴度为 3200 的 5 名妇女都有轻微发烧。因此，年龄（≥39 岁，P 值：0.01）差异具有统计学意义。此外，我们认为有必要开展更多的流行病学研究，以更好地了解孕妇的 VL 感染状况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Parasite Epidemiology and Control Medicine-Infectious Diseases

CiteScore

5.70

自引率

3.10%

发文量

审稿时长

17 weeks

期刊介绍： Parasite Epidemiology and Control is an Open Access journal. There is an increasing amount of research in the parasitology area that analyses the patterns, causes, and effects of health and disease conditions in defined populations. This epidemiology of parasite infectious diseases is predominantly studied in human populations but also spans other major hosts of parasitic infections and as such this journal will have a broad remit. We will focus on the major areas of epidemiological study including disease etiology, disease surveillance, drug resistance and geographical spread and screening, biomonitoring, and comparisons of treatment effects in clinical trials for both human and other animals. We will also look at the epidemiology and control of vector insects. The journal will also cover the use of geographic information systems (Epi-GIS) for epidemiological surveillance which is a rapidly growing area of research in infectious diseases. Molecular epidemiological approaches are also particularly encouraged.