Clinical profiles of adolescent personality pathology: a latent structure examination of the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1) in a help-seeking sample

IF 4 2区 医学 Q1 PSYCHIATRY
Madelyn Thomson, Marialuisa Cavelti, Stefan Lerch, Julian Koenig, Corinna Reichl, Ines Mürner-Lavanchy, Andrea Wyssen, Michael Kaess
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Abstract

Despite the introduction of dimensional conceptualisations of personality functioning in the latest classification systems, such as Criterion A of the Alternative Model of Personality Disorders in the DSM-5, heterogeneous clinical presentation of personality pathology remains a challenge. Relatedly, the latent structure of personality pathology as assessed by the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1) has not yet been comprehensively examined in adolescents. Therefore, this study aimed to examine the latent structure of the STiP-5.1, and, based on those findings, to describe any unique clinical profiles that might emerge. The final sample comprised 502 participants aged 11–18 years consecutively recruited from a specialised personality disorder outpatient service, as well as general day clinic and inpatient wards at the University Hospital University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University Hospital Bern, Switzerland. Participants were assessed using the STiP-5.1, as well as a battery of other psychological measures by clinical psychologists or trained doctoral students. Variations of Factor Analysis, Latent Class Analysis and Factor Mixture Models (FMM) were applied to the STiP-5.1 to determine the most appropriate structure. The best fitting model was an FMM comprising four-classes and two factors (corresponding to self- and interpersonal-functioning). The classes differed in both overall severity of personality functioning impairment, and in their scores and clinical relevance on each element of the STiP-5.1. When compared to the overall sample, classes differed in their unique clinical presentation: class 1 had low impairment, class 2 had impairments primarily in self-functioning with high depressivity, class 3 had mixed levels of impairment with emerging problems in identity and empathy, and class 4 had severe overall personality functioning impairment. A complex model incorporating both dimensional and categorical components most adequately describes the latent structure of the STiP-5.1 in our adolescent sample. We conclude that Criterion A provides clinically useful information beyond severity (as a dimensional continuum) alone, and that the hybrid model found for personality functioning in our sample warrants further attention. Findings can help to parse out clinical heterogeneity in personality pathology in adolescents, and help to inform early identification and intervention efforts.
青少年人格病理学的临床特征:在求助样本中对 DSM-5 人格功能半结构化访谈(STiP-5.1)进行潜结构检查
尽管在最新的分类系统中引入了人格功能的维度概念,如《DSM-5》中人格障碍替代模式的标准 A,但人格病理学的异质性临床表现仍然是一项挑战。与此相关的是,DSM-5 人格功能半结构化访谈(STiP-5.1)所评估的人格病理学潜在结构尚未在青少年中得到全面研究。因此,本研究旨在考察 STiP-5.1 的潜在结构,并在此基础上描述可能出现的独特临床特征。最终样本包括 502 名参与者,年龄在 11-18 岁之间,他们是从瑞士伯尔尼大学医院儿童和青少年精神病学和心理治疗医院的人格障碍专科门诊、普通日间诊所和住院病房连续招募的。临床心理学家或训练有素的博士生使用 STiP-5.1 以及一系列其他心理测量方法对参与者进行了评估。对 STiP-5.1 采用了不同的因子分析、潜类分析和因子混合模型 (FMM),以确定最合适的结构。最合适的模型是由四个类别和两个因子(分别对应于自我功能和人际功能)组成的 FMM。这些类别在人格功能障碍的总体严重程度以及在 STiP-5.1 各要素上的得分和临床相关性方面都有所不同。与总体样本相比,各分级的独特临床表现各不相同:分级 1 的人格功能损害程度较低;分级 2 主要在自我功能方面存在损害,同时伴有高度抑郁;分级 3 的人格功能损害程度参差不齐,同时伴有身份认同和移情方面的新问题;分级 4 则存在严重的总体人格功能损害。在我们的青少年样本中,一个包含维度和分类成分的复杂模型能最充分地描述 STiP-5.1 的潜在结构。我们的结论是,标准 A 所提供的临床有用信息不仅仅局限于严重程度(作为一个连续的维度),在我们的样本中发现的人格功能混合模型值得进一步关注。研究结果有助于分析青少年人格病理学的临床异质性,并为早期识别和干预工作提供依据。
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来源期刊
CiteScore
6.00
自引率
9.80%
发文量
30
审稿时长
28 weeks
期刊介绍: Borderline Personality Disorder and Emotion Dysregulation provides a platform for researchers and clinicians interested in borderline personality disorder (BPD) as a currently highly challenging psychiatric disorder. Emotion dysregulation is at the core of BPD but also stands on its own as a major pathological component of the underlying neurobiology of various other psychiatric disorders. The journal focuses on the psychological, social and neurobiological aspects of emotion dysregulation as well as epidemiology, phenomenology, pathophysiology, treatment, neurobiology, genetics, and animal models of BPD.
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