Adult brain tumour research in 2024: Status, challenges and recommendations

IF 4 2区医学 Q1 CLINICAL NEUROLOGY

Neuropathology and Applied Neurobiology Pub Date : 2024-04-12 DOI:10.1111/nan.12979

Karin Purshouse, Helen J. Bulbeck, Alasdair G. Rooney, Karen E. Noble, Ross D. Carruthers, Gerard Thompson, Petra Hamerlik, Christina Yap, Kathreena M. Kurian, Sarah J. Jefferies, Juanita S. Lopez, Michael D. Jenkinson, C. Oliver Hanemann, Lucy F. Stead

引用次数: 0

Abstract

In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro‐oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross‐cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.

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2024 年的成人脑肿瘤研究：现状、挑战和建议

2015 年，脑肿瘤患者、护理者和慈善机构的积极行动迫使英国生命科学部长成立了一个脑肿瘤研究工作组。其结果是，2018 年，英国政府承诺提供 2000 万英镑的资金，英国癌症研究中心（Cancer Research UK）也将提供 2500 万英镑的资金，专门用于随后 5 年的神经肿瘤学研究。在此，我们回顾了英国成人脑肿瘤研究的格局在这段时间内是否发生了变化，以及发生了怎样的变化，还存在哪些挑战和瓶颈。我们确定了七项通用脑肿瘤研究优先事项和三个横向主题，这些优先事项和主题涵盖了从实验室到临床再到临床的所有研究领域。我们针对英国的具体情况，讨论了每项研究的现状、挑战和建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuropathology and Applied Neurobiology 医学-病理学

CiteScore

8.20

自引率

2.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Neuropathology and Applied Neurobiology is an international journal for the publication of original papers, both clinical and experimental, on problems and pathological processes in neuropathology and muscle disease. Established in 1974, this reputable and well respected journal is an international journal sponsored by the British Neuropathological Society, one of the world leading societies for Neuropathology, pioneering research and scientific endeavour with a global membership base. Additionally members of the British Neuropathological Society get 50% off the cost of print colour on acceptance of their article.