LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes

IF 14.6 1区生物学 Q1 CELL BIOLOGY

Autophagy Pub Date : 2024-04-02 DOI:10.1080/15548627.2024.2338573

Baptiste Pradel, Guilhem Cantaloube, Marie Villares, Maïka S. Deffieu, Véronique Robert-Hebmann, Vincent Lucansky, Mathias Faure, Nathalie Chazal, Raphaël Gaudin, Lucile Espert

引用次数: 0

Abstract

HIV-1 entry into CD4+ T lymphocytes relies on the viral and cellular membranes’ fusion, leading to viral capsid delivery in the target cell cytoplasm. Atg8/LC3B conjugation to lipids, process named...

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LC3B 连接机制促进 CD4+ T 淋巴细胞中不依赖于自噬的 HIV-1 进入

HIV-1进入CD4+ T淋巴细胞依赖于病毒膜和细胞膜的融合，从而导致病毒帽载体进入靶细胞胞质。Atg8/LC3B与脂质结合的过程被命名为 "Atg8/LC3B"。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Autophagy 生物-细胞生物学

CiteScore

21.30

自引率

2.30%

发文量

277

审稿时长

1 months

期刊介绍： Autophagy is a peer-reviewed journal that publishes research on autophagic processes, including the lysosome/vacuole dependent degradation of intracellular material. It aims to be the premier journal in the field and covers various connections between autophagy and human health and disease, such as cancer, neurodegeneration, aging, diabetes, myopathies, and heart disease. Autophagy is interested in all experimental systems, from yeast to human. Suggestions for specialized topics are welcome. The journal accepts the following types of articles: Original research, Reviews, Technical papers, Brief Reports, Addenda, Letters to the Editor, Commentaries and Views, and Articles on science and art. Autophagy is abstracted/indexed in Adis International Ltd (Reactions Weekly), EBSCOhost (Biological Abstracts), Elsevier BV (EMBASE and Scopus), PubMed, Biological Abstracts, Science Citation Index Expanded, Web of Science, and MEDLINE.