Si–rhodamine derivative with a large stokes shift for ELISA-based detection of SARS-CoV-2†

IF 3.5 Q2 CHEMISTRY, ANALYTICAL
Yan-Hong Liu, Hong Zhang, Kang-Kang Yu, Xiao-Fang Pei, Jia-Nan Xu, Shan-Yong Chen, Xiao-Qi Yu and Kun Li
{"title":"Si–rhodamine derivative with a large stokes shift for ELISA-based detection of SARS-CoV-2†","authors":"Yan-Hong Liu, Hong Zhang, Kang-Kang Yu, Xiao-Fang Pei, Jia-Nan Xu, Shan-Yong Chen, Xiao-Qi Yu and Kun Li","doi":"10.1039/D4SD00038B","DOIUrl":null,"url":null,"abstract":"<p >In view of the worldwide impact of SARS-CoV-2, developing rapid and accurate ELISA-based methods for detecting SARS-CoV-2 is of great importance for diagnosing and controlling coronavirus disease 2019. Herein, we report highly stable and fluorescently bright Si–rhodamine analogues with obviously improved Stokes shifts for IgG antibody labelling. These new fluorescent dye labels provide a promising fluorescence tool for SARS-Cov-2 detection.</p>","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d4sd00038b?page=search","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensors & diagnostics","FirstCategoryId":"1085","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/sd/d4sd00038b","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

Abstract

In view of the worldwide impact of SARS-CoV-2, developing rapid and accurate ELISA-based methods for detecting SARS-CoV-2 is of great importance for diagnosing and controlling coronavirus disease 2019. Herein, we report highly stable and fluorescently bright Si–rhodamine analogues with obviously improved Stokes shifts for IgG antibody labelling. These new fluorescent dye labels provide a promising fluorescence tool for SARS-Cov-2 detection.

Abstract Image

具有大斯托克斯偏移的 Si-Rhodamine 衍生物,用于基于 ELISA 检测 SARS-CoV-2
开发基于酶联免疫吸附试验(ELISA)的快速、准确的 SARS-Cov-2 检测方法对疾病的诊断和控制具有极其重要的意义。在此,我们报告了一种高稳定性和高亮度的 Si-Rhodamine 类似物,其用于 IgG 抗体标记的斯托克斯位移有明显改善。这种新型标记荧光染料为 SARS-Cov-2 的检测提供了一种前景广阔的荧光工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
2.30
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信