Characteristics of non-fasting patients with diabetes type 2 in the DAR global surveys of 2020 and 2022

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Bachar Afandi , Khadija Hafidh , Rachid Malek , M Yakoob Ahmedani , Inass Shaltout , Reem Alamoudi , Zanariah Hussein , Mohamed Hassanein
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引用次数: 0

Abstract

Introduction

The decision to fast or not is quite complex. Personal, medical and religious matters may influence it for individuals with diabetes. However, a diagnosis of diabetes does not constitute an automatic exemption from Ramadan fasting. We aimed to evaluate the characteristics of the non-fasting cohort and explore the potential reasons during Ramadan through the global Ramadan surveys of 2020 and 2022.

Method

The Diabetes and Ramadan (DaR) Global Study is an observational retrospective survey conducted between 2020 and 2022, which included adult patients (18 and older) who fasted and those who opted not to fast. The survey captured demographic data and patient characteristics (co-morbidities, duration and type of diabetes, diabetes-related complications and medications, development of acute complications during Ramadan, hospitalisations and ER visits) for both groups.

Results

Of 12,059 patients, 1822 (14.5 %) did not fast during Ramadan; that population leaned towards females (54.6 %). They had an average age of 60.58 years (SD=12.12) with a statistically significant difference from the fasting population, averaging 54.29±11.45 (p = 0.000). Also of note was the more significant average duration of diabetes in the non-fasting cohort (12.54 years vs 9.44). There are notable regional differences in rates of fasting that ranged between 6.3 % and up to 51.2 % of patients opting not fast in certain regions (Chart 1). The risk factors that showed apparent differences of high statistical significance (p ≤ 0.001) included: long duration of diabetes of over ten years, age above 60+ years, HbA1c value over 9 %, use of insulin therapy, and being affected by one or more vascular complications (these include CKD, CVD, and diabetic foot problems).

Conclusions

Many factors and comorbidities might influence patients’ decisions when planning Ramadan fasting. The non-fasting population's demographic and clinical profiles reveal distinctive features, emphasising a need for tailored risk assessments. Furthermore, regional disparities in the decision to fast underscore the multifaceted nature of this decision-making process. The new IDF-DAR risk assessment tool can help to stratify patients’ risk during Ramadan fasting and bridge the gap among different populations and cultures.

2020 年和 2022 年 DAR 全球调查中 2 型糖尿病非空腹患者的特征
导言:禁食与否的决定相当复杂。个人、医疗和宗教因素都会影响糖尿病患者的斋戒。然而,糖尿病的诊断并不构成对斋月禁食的自动豁免。我们旨在通过 2020 年和 2022 年的全球斋月调查,评估不禁食人群的特征,并探讨斋月期间的潜在原因。方法糖尿病与斋月(DaR)全球研究是一项观察性回顾调查,于 2020 年至 2022 年期间进行,调查对象包括禁食和不禁食的成年患者(18 岁及以上)。调查收集了两组患者的人口统计学数据和患者特征(合并疾病、糖尿病病程和类型、糖尿病相关并发症和用药、斋月期间急性并发症的发生、住院和急诊就诊情况)。他们的平均年龄为 60.58 岁(SD=12.12),与禁食人群的平均年龄(54.29±11.45)有显著的统计学差异(P=0.000)。同样值得注意的是,非空腹人群的平均糖尿病病程更长(12.54 年 vs 9.44 年)。空腹率存在明显的地区差异,某些地区选择不空腹的患者比例从 6.3% 到 51.2% 不等(图 1)。具有高度统计学意义(p ≤ 0.001)的明显差异的风险因素包括:糖尿病病程超过 10 年、年龄超过 60 岁、HbA1c 值超过 9%、使用胰岛素治疗以及患有一种或多种血管并发症(包括慢性肾功能衰竭、心血管疾病和糖尿病足问题)。非斋戒人群的人口和临床特征显示出与众不同的特点,强调了进行有针对性的风险评估的必要性。此外,禁食决定的地区差异也凸显了这一决策过程的多面性。新的 IDF-DAR 风险评估工具有助于对患者在斋月禁食期间的风险进行分层,并缩小不同人群和文化之间的差距。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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