{"title":"Cashiers and bisphenols: Occupational exposure and health implications in south China","authors":"Zhenni Zhu , Yanan Pan , Xiang Chen , Xin Wei , Xiaoyue Zhou , Zixiong Tang , Renli Yin , Xiaoyang Jiao , Adela Jing Li","doi":"10.1016/j.emcon.2024.100341","DOIUrl":null,"url":null,"abstract":"<div><p>Bisphenols are ubiquitous chemicals used in various industries, raising concerns due to their potential to disrupt endocrine systems, particularly among occupational populations. This study concurrently assessed bisphenol A (BPA) and its 12 analogues in 325 urine samples from cashiers and non-cashiers residing in South China. Results revealed that BPA was the most prevalent bisphenol in urine, subsequent to bisphenol S (BPS), bisphenol F, bisphenol AF (BPAF) and bisphenol E (BPE), with detection frequencies at 60−99%. BPA exhibited the highest median concentration of 1.16 ng/mL. Urine samples from cashiers showed relatively high levels of BPA, BPS and BPE, highlighting potential occupational exposure implications. Variations in urinary bisphenol concentrations across gender and age groups were explored. Significant correlations were identified between urinary BPA and BPE, as well as BPS and BPAF, indicative of shared exposure sources and pathways. Cashiers had 1.50–13.4 times higher exposure than non-cashiers to these bisphenols. The median exposure to five bisphenols exceeded the established tolerable daily intake for BPA, set at 0.2 ng/kg bw/day, by 1.10–180 times. This study underscores the urgent need for assessing the potential health implications of bisphenol exposure, especially for high-exposure groups like cashiers, and suggests actions to reduce these risks.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":null,"pages":null},"PeriodicalIF":5.3000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000428/pdfft?md5=3d7fe8afbbf8129a044993a81441cc10&pid=1-s2.0-S2405665024000428-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emerging Contaminants","FirstCategoryId":"1087","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405665024000428","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Bisphenols are ubiquitous chemicals used in various industries, raising concerns due to their potential to disrupt endocrine systems, particularly among occupational populations. This study concurrently assessed bisphenol A (BPA) and its 12 analogues in 325 urine samples from cashiers and non-cashiers residing in South China. Results revealed that BPA was the most prevalent bisphenol in urine, subsequent to bisphenol S (BPS), bisphenol F, bisphenol AF (BPAF) and bisphenol E (BPE), with detection frequencies at 60−99%. BPA exhibited the highest median concentration of 1.16 ng/mL. Urine samples from cashiers showed relatively high levels of BPA, BPS and BPE, highlighting potential occupational exposure implications. Variations in urinary bisphenol concentrations across gender and age groups were explored. Significant correlations were identified between urinary BPA and BPE, as well as BPS and BPAF, indicative of shared exposure sources and pathways. Cashiers had 1.50–13.4 times higher exposure than non-cashiers to these bisphenols. The median exposure to five bisphenols exceeded the established tolerable daily intake for BPA, set at 0.2 ng/kg bw/day, by 1.10–180 times. This study underscores the urgent need for assessing the potential health implications of bisphenol exposure, especially for high-exposure groups like cashiers, and suggests actions to reduce these risks.
双酚是一种普遍存在于各行各业的化学品,由于其可能扰乱内分泌系统(尤其是在职业人群中),因此引起了人们的关注。本研究同时评估了华南地区 325 份收银员和非收银员尿样中的双酚 A(BPA)及其 12 种类似物。结果显示,双酚 A 是尿液中最常见的双酚,其次是双酚 S(BPS)、双酚 F、双酚 AF(BPAF)和双酚 E(BPE),检出率为 60-99%。双酚 AF (BPAF) 和双酚 E (BPE) 的检测频率为 60-99%,其中双酚 AF 的中位浓度最高,为 1.16 纳克/毫升。收银员的尿样显示出相对较高的双酚 A、双酚 BPS 和双酚 E 含量,凸显了职业暴露的潜在影响。研究还探讨了不同性别和年龄组尿液中双酚浓度的变化。尿液中的双酚 A 和双酚 BPE 以及双酚 S 和双酚 F 之间存在显著的相关性,表明存在共同的接触源和接触途径。收银员接触这些双酚的比例是非收银员的 1.50-13.4 倍。五种双酚暴露量的中位数超过了双酚 A 规定的每日可容忍摄入量(0.2 纳克/千克体重/天)的 1.10-180 倍。这项研究强调,迫切需要评估双酚暴露对健康的潜在影响,特别是对收银员等高暴露群体的影响,并建议采取行动降低这些风险。
期刊介绍:
Emerging Contaminants is an outlet for world-leading research addressing problems associated with environmental contamination caused by emerging contaminants and their solutions. Emerging contaminants are defined as chemicals that are not currently (or have been only recently) regulated and about which there exist concerns regarding their impact on human or ecological health. Examples of emerging contaminants include disinfection by-products, pharmaceutical and personal care products, persistent organic chemicals, and mercury etc. as well as their degradation products. We encourage papers addressing science that facilitates greater understanding of the nature, extent, and impacts of the presence of emerging contaminants in the environment; technology that exploits original principles to reduce and control their environmental presence; as well as the development, implementation and efficacy of national and international policies to protect human health and the environment from emerging contaminants.