State-dependent effects of repetitive transcranial magnetic stimulation on symptom dimensions of obsessive-compulsive disorder: A case report

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1016/j.jocrd.2024.100876

Wellington Chang , Ruibei Li , Barbara Van Noppen, Adam C. Frank

引用次数: 0

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation procedure that is FDA-cleared for treating obsessive-compulsive disorder (OCD). Evidence suggests that controlling brain state during rTMS treatment can influence treatment outcomes. We present the case of a patient with refractory OCD who received symptom provocation immediately preceding rTMS treatment sessions. The patient experienced more subjective and objective improvement in OCD symptoms targeted by provocations than in other symptom domains. These results suggest the importance of brain state during rTMS and could be used to guide and optimize neuromodulation treatment for OCD.

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重复经颅磁刺激对强迫症症状维度的状态依赖效应：病例报告

重复经颅磁刺激（rTMS）是一种非侵入性神经调节程序，已获得美国食品及药物管理局（FDA）批准用于治疗强迫症（OCD）。有证据表明，在经颅磁刺激治疗过程中控制大脑状态可影响治疗效果。我们介绍了一名难治性强迫症患者的病例，该患者在接受经颅磁刺激治疗之前立即接受了症状激惹治疗。与其他症状领域相比，该患者在激惹所针对的强迫症症状方面得到了更多的主观和客观改善。这些结果表明了经颅磁刺激过程中大脑状态的重要性，可用于指导和优化强迫症的神经调节治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.