State-dependent effects of repetitive transcranial magnetic stimulation on symptom dimensions of obsessive-compulsive disorder: A case report

IF 1.9 4区医学 Q3 PSYCHIATRY

Journal of Obsessive-Compulsive and Related Disorders Pub Date : 2024-04-01 DOI:10.1016/j.jocrd.2024.100876

Wellington Chang , Ruibei Li , Barbara Van Noppen, Adam C. Frank

引用次数: 0

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation procedure that is FDA-cleared for treating obsessive-compulsive disorder (OCD). Evidence suggests that controlling brain state during rTMS treatment can influence treatment outcomes. We present the case of a patient with refractory OCD who received symptom provocation immediately preceding rTMS treatment sessions. The patient experienced more subjective and objective improvement in OCD symptoms targeted by provocations than in other symptom domains. These results suggest the importance of brain state during rTMS and could be used to guide and optimize neuromodulation treatment for OCD.

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重复经颅磁刺激对强迫症症状维度的状态依赖效应：病例报告

重复经颅磁刺激（rTMS）是一种非侵入性神经调节程序，已获得美国食品及药物管理局（FDA）批准用于治疗强迫症（OCD）。有证据表明，在经颅磁刺激治疗过程中控制大脑状态可影响治疗效果。我们介绍了一名难治性强迫症患者的病例，该患者在接受经颅磁刺激治疗之前立即接受了症状激惹治疗。与其他症状领域相比，该患者在激惹所针对的强迫症症状方面得到了更多的主观和客观改善。这些结果表明了经颅磁刺激过程中大脑状态的重要性，可用于指导和优化强迫症的神经调节治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obsessive-Compulsive and Related Disorders PSYCHIATRY-

CiteScore

4.00

自引率

5.60%

发文量

审稿时长

47 days

期刊介绍： Journal of Obsessive-Compulsive and Related Disorders (JOCRD) is an international journal that publishes high quality research and clinically-oriented articles dealing with all aspects of obsessive-compulsive disorder (OCD) and related conditions (OC spectrum disorders; e.g., trichotillomania, hoarding, body dysmorphic disorder). The journal invites studies of clinical and non-clinical (i.e., student) samples of all age groups from the fields of psychiatry, psychology, neuroscience, and other medical and health sciences. The journal''s broad focus encompasses classification, assessment, psychological and psychiatric treatment, prevention, psychopathology, neurobiology and genetics. Clinical reports (descriptions of innovative treatment methods) and book reviews on all aspects of OCD-related disorders will be considered, as will theoretical and review articles that make valuable contributions. Suitable topics for manuscripts include: -The boundaries of OCD and relationships with OC spectrum disorders -Validation of assessments of obsessive-compulsive and related phenomena -OCD symptoms in diverse social and cultural contexts -Studies of neurobiological and genetic factors in OCD and related conditions -Experimental and descriptive psychopathology and epidemiological studies -Studies on relationships among cognitive and behavioral variables in OCD and related disorders -Interpersonal aspects of OCD and related disorders -Evaluation of psychological and psychiatric treatment and prevention programs, and predictors of outcome.