Hair hormone data from Syrian refugee children: Perspectives from a two-year longitudinal study

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM
Andrew K. May , Demelza Smeeth , Fiona McEwen , Patricia Moghames , Elie Karam , Michael J. Rieder , Abdelbaset A. Elzagallaai , Stan van Uum , Michael Pluess
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引用次数: 0

Abstract

For numerous issues of convenience and acceptability, hair hormone data have been increasingly incorporated in the field of war trauma and forced displacement, allowing retrospective examination of several biological metrics thought to covary with refugees’ mental health. As a relatively new research method, however, there remain several complexities and uncertainties surrounding the use of hair hormones, from initial hair sampling to final statistical analysis, many of which are underappreciated in the extant literature, and restrict the potential utility of hair hormones. To promote awareness, we provide a narrative overview of our experiences collecting and analyzing hair hormone data in a large cohort of Syrian refugee children (n = 1594), across two sampling waves spaced 12 months apart. We highlight both the challenges faced, and the promising results obtained thus far, and draw comparisons to other prominent studies in this field. Recommendations are provided to future researchers, with emphasis on longitudinal study designs, thorough collection and reporting of hair-related variables, and careful adherence to current laboratory guidelines and practices.

叙利亚难民儿童的毛发激素数据:两年纵向研究的视角
由于方便性和可接受性等诸多问题,头发激素数据越来越多地被纳入战争创伤和被迫流离 失所研究领域,从而可以对一些被认为与难民心理健康有关的生物指标进行回顾性研究。然而,作为一种相对较新的研究方法,从最初的毛发取样到最终的统计分析,毛发激素的使用仍存在一些复杂性和不确定性,其中许多问题在现有文献中未得到充分重视,限制了毛发激素的潜在作用。为了提高人们的认识,我们概述了在叙利亚难民儿童(n = 1594)中收集和分析毛发激素数据的经验,其中两次采样间隔为 12 个月。我们强调了所面临的挑战和迄今为止所取得的可喜成果,并与该领域的其他著名研究进行了比较。我们还向未来的研究人员提出了建议,重点是纵向研究设计、彻底收集和报告与头发有关的变量,以及认真遵守当前的实验室指南和实践。
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来源期刊
Comprehensive psychoneuroendocrinology
Comprehensive psychoneuroendocrinology Psychiatry and Mental Health
CiteScore
3.10
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0.00%
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审稿时长
62 days
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