Global post-mortem tissue donation programmes to accelerate cancer research

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2024-04-08 DOI:10.1038/s41568-024-00683-w

Christine Desmedt, Lisa A Carey

引用次数: 0

Abstract

Metastatic cancer represents the main cause of death in patients with cancer. However, basic and translational research is hampered by the limited availability of metastatic samples. In this context, post-mortem tissue donation programmes represent a complementary and attractive solution. Here, we highlight the opportunities and challenges, and outline why we believe this represents a global effort. Metastatic cancer represents the main cause of death in patients with cancer, but metastasis research is hindered by the limited availability of metastatic samples. In this Comment, Desmedt and Carey highlight the opportunities and challenges of post-mortem tissue donation programmes, which represent a complementary and attractive solution to overcome many of the hurdles in metastasis research.

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加快癌症研究的全球尸检组织捐赠计划

转移性癌症是癌症患者死亡的主要原因。然而，基础研究和转化研究因转移样本有限而受到阻碍。在这种情况下，死后组织捐献计划是一种具有吸引力的补充解决方案。在此，我们强调了其中的机遇和挑战，并概述了为什么我们认为这是一项全球性的工作。转移性癌症是癌症患者的主要死因，但转移样本的有限性阻碍了转移研究。在这篇评论中，Desmedt 和 Carey 强调了死后组织捐献计划的机遇和挑战，它是克服转移研究中许多障碍的一种补充性和有吸引力的解决方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.