Assessment of Acne Severity in Adult Female Acne Patients in Relation to BMI

Reham Maher, Abdel Gaber, Emad Abdelraheem Taha, Randa Ahmed El Zohne, Diana Gamal-Esmat, Fouad Botros, Radwa M. Bakr
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Abstract

Background: Acne stands as one of the most prevalent disorders in dermatology. Acne and weight gain are thought to be clinical indicators of h yperandrogenism, and it appears that obesity is linked to increased sensitivity to androgenic hormones and more severe acne. To better manage acne sufferers, this research may help uncover any connections between the severity of acne and Body Mass Index (BMI) in adult female patients. Objectives: To determine the relation between BMI and acne severity in adult female acne patients. Methods : This is a one-year case-control study. Informed written consent was taken from 103 females who attended the dermatology, venereology, and andrology outpatient clinic at Assiut University in Assiut, Egypt, between the 1 st of April, 2022, and the 31 st of March, 2023. The case group comprised 53 adult females with acne, whereas 50 age-matched females without acne comprised the control group. The Global Acne Grading System (GAGS) was used to determine the severity of acne. Results: The BMIs of both study groups were comparable. According to the GAGS scale, 19 cases (35.8%) had mild, 18 cases (34.0%) had moderate, 14 cases (26.4%) had severe, and two cases (3.8%) had very severe acne vulgaries. BMI and acne severity showed a significant positive correlation (r=0.542, p<0.001). Conclusions : This study showed that acne severity and BMI are related. Thus, BMI may be related to acne pathogenesis and severity in adult female patients.
评估成年女性痤疮患者的痤疮严重程度与体重指数的关系
背景:痤疮是皮肤科最常见的疾病之一。痤疮和体重增加被认为是雄激素过多症的临床指标,而肥胖似乎与对雄激素的敏感性增加和更严重的痤疮有关。为了更好地管理痤疮患者,这项研究可能有助于发现成年女性患者痤疮严重程度与体重指数(BMI)之间的联系。研究目的确定成年女性痤疮患者的体重指数与痤疮严重程度之间的关系。方法:这是一项为期一年的病例对照研究。在 2022 年 4 月 1 日至 2023 年 3 月 31 日期间,在埃及阿苏特的阿苏特大学皮肤病学、性病学和泌尿学门诊就诊的 103 名女性获得了知情书面同意。病例组由 53 名患有痤疮的成年女性组成,对照组由 50 名年龄相仿的无痤疮女性组成。采用全球痤疮分级系统(GAGS)确定痤疮的严重程度。研究结果两个研究组的体重指数相当。根据全球痤疮分级系统,19 例(35.8%)为轻度痤疮,18 例(34.0%)为中度痤疮,14 例(26.4%)为重度痤疮,2 例(3.8%)为极重度痤疮。体重指数与痤疮严重程度呈显著正相关(r=0.542,p<0.001)。结论 :这项研究表明,痤疮的严重程度与体重指数有关。因此,体重指数可能与成年女性患者的痤疮发病机制和严重程度有关。
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