THE ROLE OF BIOCHEMICAL MARKERS IN SCREENING OF CERVICAL EPITHELIAL PATHOLOGY WITH DETERMINATION OF P16INK4A PROTEIN EXPRESSION

Abstract

This article describes the role of biochemical markers in the pathology of the cervical epithelium. In research 10716 women aged 25-65 years were examined (mean age 43.28±3.82 years). And in the course of the study, it was found that the expression of the P16INK4A protein by cervical epithelial cells increases the risk of epithelial metaplasia of any degree by 8.86 times, high-grade epithelial metaplasia - by 692 times, RMS by 48 times.