COVID-19 Salgını Sırasında Doğuştan Bağışıklık Yetersizliği Olan Ergenlerde Psikososyal İşlevsellik

A. Güven, Saliha Esenboğa, Melis Pehlivantürk Kızılkan, C.Sinan Aslan, A. Akarsu, Erdem Karabulut, Devrim Akdemi̇r, Nuray ÖKSÜZ KANBUR, Deniz Ayvaz, İlhan Tezcan, Orhan Derman
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Abstract

Objective: We aimed to determine the impact of COVID-19 on the psychosocial functioning of adolescents with inborn errors of immunity (IEI). Material and Methods: Thirty-six patients with IEI (18 mild, 18 severe) and 18 healthy controls aged between 10 and 17 were included in this study. Adolescents and their caregivers completed the Revised Child Anxiety and Depression Scale (RCADS) to measure symptoms of anxiety and depression and the Strengths and Difficulties Questionnaire (SDQ) to assess prosocial behaviors and emotional/behavioral problems. Additionally, the COVID-19 Phobia Scale (C19P-S) was answered by adolescents to assess the level of coronavirus phobia. Results: According to SDQ, emotional scores of the adolescents in the control group are higher than the mild/severe patient group. Emotional scores of the severe patient group are higher than the mild group. The RCADS parent- and adolescent-reported depression scores and parent-reported social phobia scores of the control group were significantly higher than the mild group.There were no statistically significant differences between the groups according to COVID-19 Phobia Scale. Conclusion: The healthy adolescents had higher psychiatric symptom scores, especially than the adolescents with mild IEI. We suggest that being exposed to health-related challenges even before the pandemics in adolescents with IEI helped them develop psychological resilience. Longitudinal and larger studies are needed to evaluate the long-term effects of the pandemic on the mental health of this vulnerable adolescent population.
COVID-19 大流行期间先天性免疫缺陷青少年的社会心理功能
目的我们旨在确定 COVID-19 对患有先天性免疫错误(IEI)的青少年社会心理功能的影响。材料与方法本研究共纳入 36 名先天性免疫错误患者(18 名轻度患者,18 名重度患者)和 18 名健康对照者,他们的年龄在 10 到 17 岁之间。青少年及其照护者填写了《修订版儿童焦虑抑郁量表》(RCADS)以测量焦虑和抑郁症状,并填写了《优势与困难问卷》(SDQ)以评估亲社会行为和情绪/行为问题。此外,青少年还回答了COVID-19恐惧症量表(C19P-S),以评估冠状病毒恐惧症的程度:根据 SDQ,对照组青少年的情绪得分高于轻度/重度患者组。重度患者组的情绪得分高于轻度患者组。对照组家长和青少年报告的 RCADS 抑郁症评分和家长报告的社交恐惧症评分明显高于轻度组:结论:健康青少年的精神症状得分较高,尤其是轻度 IEI 青少年。我们认为,患有 IEI 的青少年甚至在大流行之前就面临与健康有关的挑战,这有助于他们发展心理复原力。我们需要进行纵向和更大规模的研究,以评估大流行对这一脆弱青少年群体心理健康的长期影响。
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