Knowledge, Attitude and Ethical Perception Towards Precision Medicine Among Healthcare Professionals- a Questionnaire Survey

Dr. Nikita Kulgod, Dr. Akash Gadgade, Dr. Amirtha Tom, Mr. Pranav Mhetre
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Abstract

Precision medicine, also known as personalized medicine, is an emerging approach in healthcare that tailors medical treatment and prevention strategies to individual patients based on their unique genetic makeup, lifestyle, and environmental factors. It represents a paradigm shift from the traditional “one size fits all” approach to a more targeted and precise form of medical care. In precision medicine, extensive genomic analysis and other high-throughput technologies are employed to identify genetic variations and molecular markers associated with specific diseases or treatment responses. This wealth of genetic information allows healthcare professionals to make more accurate diagnoses, predict disease risks, and design personalized treatment plans. The application of precision medicine spans various medical fields, including oncology, cardiovascular diseases, neurology, and infectious diseases. In oncology, for example, molecular profiling of tumors enables the identification of specific genetic alterations that guide the selection of targeted therapies, leading to improved patient outcomes and reduced adverse effects. Precision medicine also holds great promise in preventive medicine. By identifying an individual’s genetic predispositions to certain diseases, clinicians can recommend tailored lifestyle modifications or interventions to mitigate the risk. Additionally, the integration of electronic health records, wearable devices, and mobile health applications facilitates real-time monitoring and personalized interventions, enhancing patient engagement and overall healthcare outcomes. Despite its potential, several challenges need to be addressed for the widespread implementation of precision medicine. These include the high cost of genomic sequencing and data analysis, ensuring data privacy and security, and the need for interdisciplinary collaboration among researchers, clinicians, and policymakers. In conclusion, precision medicine represents a transformative approach to healthcare, enabling personalized and targeted interventions that have the potential to revolutionize patient care, improve treatment outcomes, and reduce healthcare costs. Efforts to overcome the challenges associated with precision medicine are crucial for its successful integration into routine clinical practice.
医疗保健专业人员对精准医疗的认识、态度和伦理观念--问卷调查
精准医疗又称个性化医疗,是一种新兴的医疗保健方法,它根据患者独特的基因构成、生活方式和环境因素,为其量身定制医疗和预防策略。在精准医疗中,广泛的基因组分析和其他高通量技术被用来识别与特定疾病或治疗反应相关的基因变异和分子标记。这些丰富的基因信息使医护人员能够做出更准确的诊断,预测疾病风险,并设计个性化的治疗方案。精准医疗的应用横跨多个医学领域,包括肿瘤学、心血管疾病、神经学和传染病。例如,在肿瘤学领域,通过对肿瘤进行分子剖析,可以确定特定的基因改变,从而指导靶向疗法的选择,改善患者的治疗效果,减少不良反应。通过识别个人对某些疾病的遗传倾向,临床医生可以推荐有针对性的生活方式调整或干预措施,以降低风险。此外,电子健康记录、可穿戴设备和移动医疗应用的整合有助于实时监测和个性化干预,提高患者参与度和整体医疗效果。尽管精准医疗潜力巨大,但要广泛实施精准医疗,还需要应对一些挑战。这些挑战包括基因组测序和数据分析的高昂成本、确保数据隐私和安全,以及研究人员、临床医生和政策制定者之间跨学科合作的必要性。总之,精准医疗代表了一种变革性的医疗保健方法,可实现个性化和有针对性的干预,有可能彻底改变患者护理、改善治疗效果并降低医疗成本。努力克服与精准医疗相关的挑战对于将其成功融入常规临床实践至关重要。
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