COMPARISON OF FLUCONAZOLE AND GRISEOFULVIN IN TREATMENT TREATMENT OF TINEA

Abstract

Approximately a billion people are assessed to have skin,nail and hair fungal diseases; millions have mucosal candidiasis and higher than 150 million people have serious fungal diseases, which have a major effect on their lives or are deadly.Moreover,mortality associated with fungal disease at >1.6 million is like that of tuberculosis and >3-fold more than malaria. Socioeconomic, geo-ecological attributes and the rising number of at-risk people are the main factors for variation in occurrence and pervasiveness of fungal disease across the world. Fungal infections are influenced majorly by the HIV/AIDS pandemic, tuberculosis, chronic obstructive pulmonary disease, asthma and the rising occurrence of cancers in both developed and developing countries [ 1 – 4 ] worldwide. Fungal skin diseases were the most widespread skin disease globally in 2017 (10.09%) and in 2016, fungal skin diseases were ranked the fourth highest in the occurrence of disease (2.1 billion cases) when compared [5,6] to 328 different illnesses and injuries worldwide.