Impact of Non-Surgical Periodontal Therapy on HbA1c Levels of Type 2 Diabetes at Khyber College of Dentistry, Peshawar: A Quasi-Experimental Study

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Abstract

Background: Diabetes mellitus (DM) constitutes a spectrum of persistent metabolic disorders originating from irregular glucose metabolism due to insufficient insulin production, compromised insulin function, or a combination of the two, leading to elevated blood sugar levels. This study assessed the influence of non-surgical periodontal therapy on glycated hemoglobin (HbA1c) levels in individuals with Type 2 Diabetes. Methods: This quasi-experimental study was conducted at Khyber College of Dentistry, Peshawar, with 40 participants diagnosed with Type 2 diabetes for more than 3 years and suffering from chronic periodontitis. Patients with Type 1 diabetes, pregnant women, and those with other medical complications were excluded. HbA1c levels were assessed at baseline, and non-surgical periodontal therapy was administered. Patients were educated and scheduled for a follow-up after 3 months when HbA1c levels were reassessed. A paired t-test was employed to compare HbA1c levels pre-and post-intervention. Results: In this study, males were 29 (58%) whereas 21 (42%) females. The mean value of HbA1c was less post-treatment with non-surgical periodontal therapy (6.928±0.866%) than pretreatment (9.048±0.73%) and results were statistically significant (p<0.001). After receiving therapy, the HbA1c level was significantly reduced in both genders (p<0.001). Irrespective of smoking status, the reduction of HbA1c level was statistically significant (p=0.01). Conclusion: Non-surgical periodontal treatment significantly reduces HbA1c levels, indicating a potentially positive impact on glycemic control in individuals with diabetes, which has enhanced the dentist’s role as a part of the health team, and timely interventions can significantly improve prognosis.
白沙瓦开伯尔牙科学院非手术牙周治疗对 2 型糖尿病患者 HbA1c 水平的影响:准实验研究
背景:糖尿病(DM)是由于胰岛素分泌不足、胰岛素功能受损或两者共同作用导致葡萄糖代谢不正常,从而引起血糖水平升高的一系列持续性代谢紊乱。本研究评估了非手术牙周治疗对 2 型糖尿病患者糖化血红蛋白(HbA1c)水平的影响:这项准实验研究在白沙瓦的开伯尔牙科医学院进行,共有 40 名被诊断为 2 型糖尿病 3 年以上并患有慢性牙周炎的患者参加。1型糖尿病患者、孕妇和患有其他并发症的患者被排除在外。基线评估 HbA1c 水平,并进行非手术牙周治疗。对患者进行教育,并安排他们在 3 个月后复诊,再次评估 HbA1c 水平。采用配对 t 检验比较干预前后的 HbA1c 水平:在这项研究中,男性 29 人(占 58%),女性 21 人(占 42%)。非手术牙周治疗后的 HbA1c 平均值(6.928±0.866%)低于治疗前(9.048±0.73%),结果具有统计学意义(P<0.001)。接受治疗后,男女患者的 HbA1c 水平均显著降低(P<0.001)。无论吸烟与否,HbA1c 水平的降低均有统计学意义(P=0.01):结论:非手术牙周治疗可明显降低 HbA1c 水平,这表明它对糖尿病患者的血糖控制具有潜在的积极影响,从而加强了牙医作为医疗团队一部分的作用,及时干预可明显改善预后。
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