The Rate of Epidural Analgesia in Labor with Maternal And Neonatal Outcome at Tertiary Hospital in Oman

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Abstract

Objectives: The primary objective is to determine the epidural analgesia rate and its effect on the mode of delivery. The secondary objectives are to assess patient satisfaction, duration of second stage of labour and incidence of maternal, fetal and neonatal outcomes. Methods: A retrospective cohort design utilized in this study, involving all pregnant women received epidural analgesia in labour at Sultan Qaboos University Hospital over 3 years period (March 2020 to March 2023). All data is collected from the delivery register at Delivery ward, SQUH track care system, and epidural record chart. Women’s information remained confidential. All entered data in the SPSS program is stored in a passwordprotected computer. Results: There was a total of 7076 deliveries, out of which 389 received epidural analgesia, with a rate of 5.0% (95% CI: 5.0 – 6.0). Out of 389 deliveries, around half were nulliparous and the other half were multiparous. The rate of spontaneous vaginal delivery constituted 60.7%. On the other hand, instrumental deliveries and LSCS constituted 14.9% and 24.4% respectively. The median and mean (±SD) period of 2nd stage were 24.0 and 38.3±40.1. Only 1% of all included patients had prolonged second stage of labor. The rate of oxytocin use was 54.5%, and around 52.4% of it was among nulliparous. 148 patients (52.5% ) reported full benefit from epidural analgesia use, compared to 6% who reported no benefit. In addition, 12.7% of CTG showed fetal distress and postpartum hemorrhage constituted 6.7% among delivered ladies. The study showed that 10.0% of included ladies suffered one or more of post-partum complications, including fever (n 13, 3.3%), headache (n 10, 2.6%), backache (n 3, 0.8%), hypotension (n 9, 2.3%), urine retention (n 3, 0.8%), pruritus (n 1, 0.3%), and nausea and vomiting (n 1, 0.3%). 6.2% was the rate of NICU admissions among the newborns. Conclusions: The study revealed that 5% was the rate of epidural analgesia usage and spontaneous vaginal delivery was the main mode of delivery. However, the indications for delivery by cesarean section or instruments were not related to epidural analgesia in labour. In addition, there was no significant adverse effect on maternal, fetal and neonatal outcome. Based on that, we need to elaborate more on epidural analgesia awareness and usage in order to be offered. Although some previous reviewed studies reported adverse effects of epidural analgesia on labour outcome. Future researches are recommended including prospective design study, bigger sample size, wider variation and multicenter studies.
阿曼三级医院分娩硬膜外镇痛率与产妇和新生儿结局的关系
目标:首要目标是确定硬膜外镇痛率及其对分娩方式的影响。次要目标是评估患者满意度、第二产程持续时间以及产妇、胎儿和新生儿结局的发生率。研究方法本研究采用回顾性队列设计,涉及苏丹卡布斯大学医院在 3 年内(2020 年 3 月至 2023 年 3 月)接受硬膜外镇痛分娩的所有孕妇。所有数据均来自分娩病房的分娩登记簿、苏丹卡布斯大学医院跟踪护理系统和硬膜外镇痛记录表。妇女的信息保密。所有输入 SPSS 程序的数据均存储在有密码保护的计算机中。结果共有 7076 例分娩,其中 389 例接受了硬膜外镇痛,比例为 5.0%(95% CI:5.0 - 6.0)。在 389 例分娩中,约有一半是单胎分娩,另一半是多胎分娩。自然阴道分娩占 60.7%。另一方面,器械接生和顺产分别占 14.9% 和 24.4%。第二产程的中位数和平均值(±SD)分别为 24.0 和 38.3±40.1。在所有纳入的患者中,只有1%的患者第二产程延长。催产素的使用率为 54.5%,其中约 52.4%为无痛分娩。有 148 名患者(52.5%)表示从硬膜外镇痛中完全获益,只有 6% 的患者表示没有获益。此外,12.7%的 CTG 显示胎儿窘迫,产后出血的产妇占 6.7%。研究显示,10.0%的产妇患有一种或多种产后并发症,包括发烧(13 例,3.3%)、头痛(10 例,2.6%)、背痛(3 例,0.8%)、低血压(9 例,2.3%)、尿潴留(3 例,0.8%)、瘙痒(1 例,0.3%)以及恶心和呕吐(1 例,0.3%)。新生儿入住新生儿重症监护室的比例为 6.2%。结论研究显示,硬膜外镇痛的使用率为 5%,自然阴道分娩是主要的分娩方式。然而,剖宫产或器械分娩的适应症与硬膜外镇痛分娩无关。此外,硬膜外镇痛对产妇、胎儿和新生儿的结局也没有明显的不良影响。在此基础上,我们需要对硬膜外镇痛的认识和使用进行更详细的阐述,以便提供相关服务。尽管之前的一些综述研究报告了硬膜外镇痛对分娩结果的不良影响。建议未来的研究包括前瞻性设计研究、更大的样本量、更广泛的差异和多中心研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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