Vitamin D level in children with atopic dermatitis

Abstract

Aims: Atopic dermatitis is a chronic relapsing skin disease that is mostly seen between the ages of 0-5. In our study, we aimed to reveal the difference in 25-OH vitamin D levels between the patient group diagnosed with atopic dermatitis and the control group. Methods: It was carried out at the Pediatric Allergy Polyclinic of Balıkesir University Faculty of Medicine Hospital between 2018-2021. A control group consisting of 220 patients between the ages of 0-17 who were diagnosed with atopic dermatitis and who applied to the Pediatric Allergy outpatient clinic and 220 patients who were not diagnosed with atopic dermatitis were included. The diagnosis of atopic dermatitis was made using the Hanifin-Rajka criteria. Disease activity was measured by the scorad index. Results: 25-OH vitamin D level and eosinophilia value in peripheral blood were found to be statistically significant between the patient and control groups. No significant difference was found between the patient and control groups in terms of parental age, parental education level, living place, weight, height, and body mass index (BMI) . Conclusion: 25-OH vitamin D levels were found to be lower and eosinophil levels were higher in patients with atopic dermatitis . No significant difference was found in terms of total IgE ( kU /L) level. More extensive studies are needed to determine how 25-OH vitamin D (ng/dl) level affects atopic dermatitis.