Polarization-encoded 3D structured light and multifocal spot arrays generation based on metasurface

Modern Physics Letters B Pub Date : 2024-01-29 DOI:10.1142/s0217984924501860

Jiaqi Zhao, Suyang Ge, Yingbo Li, Zilei Liu, Weihua Yang, Siqi Li

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Abstract

Fluorescence microscopy possesses the advantages of high resolution, high sensitivity, molecular specificity and noninvasiveness, providing an important tool in life science research. The multifocal array and 3D structured light are two kinds of important light fields that are often used in scanning fluorescence microscopy systems and wide-field fluorescence microscopy systems. However, traditional methods for generating multifocal arrays and 3D structured light illumination rely on various bulk optical components, making it challenging to achieve compact optical systems. Besides, generating these two types of illumination typically requires two separate and independent optical systems, hindering the integration of different types of fluorescence microscopy systems. Here, a dielectric metasurface is proposed that can achieve the switching between multifocal arrays and 3D structured light through polarization state modulation, greatly simplifying the illumination optics of fluorescence microscopy systems and facilitating the integration of different types of fluorescence microscopy systems.

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基于元表面的偏振编码三维结构光和多焦光斑阵列生成技术

荧光显微镜具有高分辨率、高灵敏度、分子特异性和无损伤等优点，是生命科学研究的重要工具。多焦阵列和三维结构光是扫描荧光显微系统和宽场荧光显微系统中经常使用的两种重要光场。然而，生成多焦阵列和三维结构光照明的传统方法依赖于各种大体积光学元件，这使得实现紧凑型光学系统具有挑战性。此外，产生这两种类型的照明通常需要两个独立的光学系统，阻碍了不同类型荧光显微镜系统的集成。本文提出了一种介电元表面，它可以通过偏振态调制实现多焦阵列和三维结构光之间的切换，从而大大简化了荧光显微镜系统的照明光学系统，促进了不同类型荧光显微镜系统的集成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modern Physics Letters B

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