CONSTITUTIONAL PREDICTORS OF THE DEVELOPMENT OF LIFE-THREATENING COMPLICATIONS DURING SURGICAL TREATMENT OF AORTO-FEMORAL “C-D” TASC II LESIONS, USING LAPAROTOMIC AND RETROPERITONEAL ACCESSES

Suzdaltsev S.E., Sulimanov R.A., Sulimanov R.R., Spassky E.S., Grigoryan M.D.
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Abstract

Relevance. Currently, the use of transperitoneal and retroperitoneal approaches in surgery for lesions of the aorta and iliac arteries remains necessary. In our previous studies, we expressed an opinion about the relationship between the choice of surgical approach and the constitutional parameters of the patient based on a study of postoperative results in reconstructions of the aorto -femoral segment. We believe that the patient's constitutional parameters are one of the key factors that should be taken into account when choosing a surgical approach. Purpose of the study. Assessing the significance of the influence of the patient’s constitutional parameters on the development of life-threatening postoperative complications when using laparotomy and retroperitoneal approaches. Materials and methods. The study included 284 patients who underwent aorto-bifurcation femoral bypass/prosthetics for lesions of the aorta and iliac arteries of types C and D according to the international classification TASC II. The patients were divided into groups according to the surgical approach used: group I (n = 160) - laparotomic approach, group II (n = 124) - retroperitoneal approach, according to C. Rob. In the groups, the number of development of life-threatening complications of stage III - IV was assessed according to the Clavien - Dindo classification and deaths. Between patients with and without the development of the above-described complications in groups I and II, the values of constitutional parameters were compared, which allow assessing the presence or absence of excess body weight and the type of visceral obesity of the patient, based on the patient’s skeletal structure: height, weight, body mass index, abdominal circumference, cost-iliac distance, epigastric angle, xiphoid-pubic distance. Results. A comparative analysis of the total number of development of life-threatening complications and mortality did not show a significant difference between patients in the studied groups, however, the number of development of gastrointestinal complications in group II was significantly lower than in group I, and amounted to 1 (0.8%) vs 10 (6.2%) respectivelyclinical observations (p* = 0.019). The Kruskal-Wallis analysis revealed that the indicators: weight, BMI, abdominal circumference, costal - iliac distance and epigastric angle, have a significant difference between patients with and without life-threatening complications in groups I and II (p*** < 0.05), while height and xiphoid-pubic distance did not confirm the statistical significance of their influence on the development of such complications in the studied groups. Conclusion. Constitutional parameters: weight, body mass index, costoiliac distance, abdominal circumference and epigastric angle have a statistically significant effect on the development of postoperative life-threatening complications when using laparotomy and retroperitoneal approaches. Based on the results of the study, a table was generated for selecting the optimal surgical approach based on an assessment of the patient’s constitutional parameters.
使用腹腔镜和腹膜后入路手术治疗主动脉-股动脉 "C-D "TASC II 病变期间出现危及生命的并发症的宪法预测因素
相关性。目前,在主动脉和髂动脉病变的手术中仍有必要使用经腹膜和腹膜后入路。在之前的研究中,我们根据对主动脉-股动脉段重建手术术后结果的研究,就手术方式的选择与患者体质参数之间的关系发表了看法。我们认为,患者的体质参数是选择手术方式时应考虑的关键因素之一。评估在使用开腹和腹膜后方法时,患者的体质参数对发生危及生命的术后并发症的影响意义。研究纳入了284名根据国际分类TASC II对C型和D型主动脉和髂动脉病变进行股主动脉分叉旁路术/假体植入术的患者。根据采用的手术方式将患者分为两组:第一组(n = 160)--开腹手术,第二组(n = 124)--腹膜后手术。根据 Clavien - Dindo 分类法,评估了各组中出现 III - IV 期危及生命并发症的人数和死亡人数。对第一组和第二组中出现和未出现上述并发症的患者的体征参数值进行了比较,根据患者的骨骼结构来评估是否存在体重超标和内脏肥胖类型:身高、体重、体重指数、腹围、肋距、上腹角、剑突-耻骨间距。对危及生命的并发症发生总数和死亡率进行比较分析后发现,各研究组患者之间并无明显差异,但第二组患者发生胃肠道并发症的数量明显低于第一组,分别为 1 例(0.8%)和 10 例(6.2%)临床观察(P* = 0.019)。Kruskal-Wallis分析显示,体重、体重指数、腹围、肋骨-髂骨距离和上腹部角度等指标在I组和II组出现和未出现危及生命并发症的患者之间存在显著差异(p*** < 0.05),而身高和剑突-耻骨间距对研究组出现此类并发症的影响不具有统计学意义。体重、体重指数、髂肋距离、腹围和上腹部角度等体格参数对采用开腹和腹膜后方法进行手术时出现危及生命的术后并发症有显著的统计学影响。根据研究结果生成了一个表格,用于根据对患者体质参数的评估选择最佳手术方法。
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