RELATIONSHIP OF CARBOXYHEMOGLOBIN (COHB) AND HEMOGLOBIN (HB) LEVELS IN ACTIVE SMOKERS IN GRESIK REGENCY

Abstract

Smoking habits in society are still often found among adults, adolescents, and even young children. It is known that these habits have a negative impact on the body and can cause death. There are a number of chemicals in cigarettes that cause symptoms of health problems, one of which is carbon monoxide (CO). Carbon monoxide, in the form of a gas due to combustion from cigarettes, is inhaled and enters the lungs and the bloodstream. CO gas will bind hemoglobin in the same place where oxygen binds hemoglobin, thus forming carboxyhemoglobin (COHb). This can happen because the binding force of CO is stronger than the binding power of O2 on Hb. The purpose of this study was to analyze the relationship between Carboxyhemoglobin levels and Hemoglobin levels in active smokers in Gresik Regency. This study was an analytical observational study with a cross sectional design conducted at the Toxicology and Hematology Laboratory of the Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, from October 2022 to June 2023. Blood tests were carried out on 30 active smokers with purposive sampling techniques. The results showed an average COHb level of 0.89%; average hemoglobin level of 14.6 g/dL. The data results were analyzed using the SPSS program. The conclusion of this reseach was that there was no relationship between COHb and Hemoglobin in active smokers in Gresik Regency.