Glomerular Herniation in Toxemia of Pregnancy before 18 Weeks Gestation

Abstract

Presentation of preeclampsia before 18 weeks is rare. We present a case of severe preeclampsia manifesting at 18 weeks gestation, notable with concurrent renal and optic changes. Beyond the typical kidney histological features of toxemia of pregnancy, the kidney biopsy revealed a distinctive histopathological finding-herniation of the glomerular tuft into the proximal tubule. This finding is rare with only a few cases reported in the literature. We present our findings for the early identification of preeclampsia. Additionally, our case exhibited severe retinal edema on fundoscopy, also offering a potential avenue for improving early detection. These insights are crucial for further exploration and understanding of these unique aspects of early preeclampsia just prior to retinal detachment.