A PROSPECTIVE STUDY TO EVALUATE THE ROLE OF MONOCYTE TO LYMPHOCYTE RATIO AS A PREDICTOR OF ACUTE TRAUMATIC INTRAPARENCHYMAL HEMORRHAGE EXPANSION AFTER CEREBRAL CONTUSION

Abstract

Background: The present study was conducted to evaluate the role of monocyte to lymphocyte ratio as a predictor of acute traumatic intraparenchymal hemorrhage expansion after cerebral contusion. Materials and methods: A total of 300 patients diagnosed with primary cerebral contusion were included in the study. Demographic parameters, mode and severity of the injury,signs and symptoms pupillary reactions and Glasgow Coma Scale scores were recorded.MLR was obtained from routine blood tests and baseline and follow-up (within 24 hrs) hematoma volumes was calculated from the CT images using semi-automated computer-assisted volumetric analysis. Fisher's exact test, Pearson's chi square test, independent t test and logistic regression were used for statistical analysis. Results: Both baseline and follow-up tICH volumes significantly higher in patients with acute tICH expansion (p=0.016 and p=0.004 respectively). The MLR was significantly higher in the patients with acute tICH expansion (p=0.001). Conclusion: MLR at hospital admission can be used as a significant factor to predict acute traumatic tICH expansion after cerebral contusion.