Prevalence and Predicting Factors of Pretreatment Dysphagia in Veterans With Head and Neck Cancer: A Pilot Study

Heather L. Warner, Lauren Romanelli, Katherine Adams, Jingyuan Xiao, Nwanmegha Young
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Abstract

Dysphagia is a common sequela in individuals with a diagnosis of head and neck cancer. However, the prevalence and predicting factors for pretreatment dysphagia have not been well identified in the literature. A priori knowledge of the presence of a pretreatment dysphagia is advantageous and can have clinically significant implications for management of this patient population. The ability to predict pretreatment dysphagia in this population would allow more targeted interventions and potential improvements in clinical outcomes. This pilot study investigated the prevalence and predicting factors of pretreatment dysphagia in 67 veterans with head and neck cancer through the West Haven, CT, Veterans Affairs cancer database. Data for this study were acquired via retrospective medical record review. The prevalence of pretreatment dysphagia in our sample was found to be 49.3%. Age and pretreatment percutaneous endoscopic gastrostomy placement were found to have a statistically significant relationship with pretreatment dysphagia. Stage of cancer diagnosis and the diagnosis of pretreatment dysphagia were found to have a statistically significant relationship with posttreatment dysphagia. Findings offer important preliminary data and clinical considerations about this issue and serve as a foundation for future research. There are a limited number of factors associated with pretreatment dysphagia, and clinicians should consider a conservative referral approach when considering the need for dysphagia assessment prior to the initiation of oncologic treatment.
头颈癌退伍军人治疗前吞咽困难的发生率和预测因素:一项试点研究
吞咽困难是头颈部癌症患者常见的后遗症。然而,文献中并未明确指出治疗前吞咽困难的发生率和预测因素。事先了解治疗前是否存在吞咽困难是有好处的,对这类患者的管理具有重要的临床意义。如果能够预测这类人群在治疗前出现的吞咽困难,就可以采取更有针对性的干预措施,并有可能改善临床疗效。 这项试验性研究通过康涅狄格州西黑文退伍军人事务部的癌症数据库,调查了 67 名患有头颈部癌症的退伍军人在治疗前出现吞咽困难的患病率和预测因素。 本研究的数据是通过回顾性病历审查获得的。 在我们的样本中,治疗前吞咽困难的发生率为 49.3%。研究发现,年龄和治疗前经皮内镜胃造瘘术与治疗前吞咽困难有显著的统计学关系。癌症诊断分期和治疗前吞咽困难诊断与治疗后吞咽困难有显著统计学关系。 研究结果为这一问题提供了重要的初步数据和临床考虑,并为今后的研究奠定了基础。与治疗前吞咽困难相关的因素数量有限,临床医生在考虑是否需要在开始肿瘤治疗前进行吞咽困难评估时,应考虑采取保守的转诊方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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