Kaposi sarcoma in an immunocompetent patient: a case report

Anjana B., Ranjeeta Sapam, Gurumayum Chitralekha Devi
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Abstract

Kaposi sarcoma (KS) is an uncommon vascular neoplasm associated with human herpes virus 8 (HHV8) infection. Lesions predominantly present at mucocutaneous sites, but may involve other organs. Epidemiological-clinical forms of KS include classic, endemic, AIDS associated and iatrogenic KS. KS is one of the most common AIDS defining malignancy. Lesions evolve from early (patch stage) macule into plaque stage and nodule stage. Diagnosis is made through clinical, histopathological findings and specific immunohistochemical markers for HHV8. Treatment is either by means of destructive procedures and systemic therapy in case of multiorgan involvement. This report is a case of classic KS in a 74-year nondiabetic, non hypertensive female, with no significant surgical, sexual or history of immunosuppression for the occurrence of KS. This case throws light on addressing KS in an immunocompetent patient or a newer variant of KS yet to be researched upon, which can go clinically misdiagnosed due to lack of significant history.
免疫功能正常患者的卡波西肉瘤:病例报告
卡波西肉瘤(KS)是一种不常见的血管肿瘤,与人类疱疹病毒 8(HHV8)感染有关。病变主要发生在皮肤粘膜部位,但也可能累及其他器官。KS 的流行病学临床形式包括典型的、地方性的、艾滋病相关的和先天性的 KS。KS 是艾滋病最常见的恶性肿瘤之一。病变从早期(斑块期)的斑点演变为斑块期和结节期。诊断可通过临床、组织病理学发现和 HHV8 的特异性免疫组化标记来进行。在多器官受累的情况下,可通过破坏性手术和全身治疗进行治疗。本报告是一例典型的 KS 病例,患者是一名 74 岁的非糖尿病、非高血压女性,没有明显的手术史、性史或免疫抑制史。本病例揭示了免疫功能正常患者的 KS 或尚待研究的 KS 新变异型,由于缺乏重要病史,临床上可能会误诊。
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