Taraxerol: A Promising Natural Product in the Management of Inflammation

Uma Jyoti, Neeraj Mittal, Thakur Gurjeet Singh, Randhir Singh, Sushma Devi
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Abstract

Inflammation is a complex biological process that plays an important role in many clinical disorders. The natural plant and its secondary metabolites play an important role in the prevention and treatment of inflammation. Taraxerol is a pentacyclic triterpenoid found in medicinal plants, fruits, and vegetables, and is a potent anti-inflammatory agent. This review explains the molecular mechanism of the anti-inflammatory effects of taraxerol and its interactions with many molecular targets, including NF-κB, MAPKs, and COX. Furthermore, the effects of taraxerol on oxidative stress, cell function, and inflammatory cell signaling have been comprehensively described. This review addresses the limitations and obstacles in taraxerol research, as well as provides insights for future investigations. The findings highlight the need for additional research to completely understand the therapeutic potential and clinical applications of taraxerol in the treatment of inflammatory diseases.
蒲公英萜醇:治疗炎症的前景广阔的天然产品
炎症是一个复杂的生物过程,在许多临床疾病中发挥着重要作用。天然植物及其次生代谢产物在预防和治疗炎症方面发挥着重要作用。蒲公英萜醇是一种存在于药用植物、水果和蔬菜中的五环三萜类化合物,是一种有效的抗炎剂。这篇综述解释了蒲公英萜醇抗炎作用的分子机理及其与 NF-κB、MAPKs 和 COX 等多种分子靶点的相互作用。此外,还全面阐述了蒲公英萜醇对氧化应激、细胞功能和炎症细胞信号传导的影响。本综述探讨了蒲公英萜醇研究的局限性和障碍,并为未来的研究提供了启示。研究结果突出表明,要完全了解蒲公英萜醇在治疗炎症性疾病方面的治疗潜力和临床应用,还需要进行更多的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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