Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-02-01 DOI:10.1016/j.eimc.2024.02.009

Daniela de la Rosa-Zamboni, Mónica Villa-Guillén, Anaíd Bustos-Hamdan, María Isabel Rosas-Mateos, Marisol Medina-Pelcastre, Margarita Torres-García, María Isabel Franco-Hernández, María del Carmen Castellanos-Cruz, Israel Parra-Ortega, Edmedt Fest-Parra, María Citlalli Casillas-Casillas, Ana Carmen Guerrero-Díaz

{"title":"Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections","authors":"Daniela de la Rosa-Zamboni, Mónica Villa-Guillén, Anaíd Bustos-Hamdan, María Isabel Rosas-Mateos, Marisol Medina-Pelcastre, Margarita Torres-García, María Isabel Franco-Hernández, María del Carmen Castellanos-Cruz, Israel Parra-Ortega, Edmedt Fest-Parra, María Citlalli Casillas-Casillas, Ana Carmen Guerrero-Díaz","doi":"10.1016/j.eimc.2024.02.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.</div></div><div><h3>Methods</h3><div>All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1+UV-C disinfection; P3: P2+Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.</div></div><div><h3>Results</h3><div>552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (<em>p</em>  =0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI<sub>95%</sub> 0.30–0.81, <em>p</em>  =0.011).</div></div><div><h3>Conclusions</h3><div>Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 64-70"},"PeriodicalIF":2.6000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Enfermedades infecciosas y microbiologia clinica","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0213005X24002088","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.

Methods

All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1 + UV-C disinfection; P3: P2 + Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.

Results

552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (p = 0.006). HCAIs with bacterial isolates dropped from 5.39/1000 PD in PI to 1.79/1000 PD in P4 (p = 0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI_95% 0.30–0.81, p = 0.005) and with lesser HCAIs with bacterial isolates (RR 0.33, CI_95% 0.14–0.77, p = 0.011).

Conclusions

Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.

查看原文本刊更多论文

紫外线-C 消毒和镀铜对 ESBL 感染率较高的新生儿重症监护室医护人员相关感染的影响

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Enfermedades infecciosas y microbiologia clinica 医学-传染病学

CiteScore

2.10

自引率

8.00%

发文量

194

审稿时长

29 days

期刊介绍： Hoy está universalmente reconocida la renovada y creciente importancia de la patología infecciosa: aparición de nuevos agentes patógenos, de cepas resistentes, de procesos con expresión clínica hasta ahora desconocida, de cuadros de una gran complejidad. Paralelamente, la Microbiología y la Infectología Clínicas han experimentado un gran desarrollo como respuesta al reto planteado por la actual patología infecciosa. Enfermedades Infecciosas y Microbiología Clínica es la Publicación Oficial de la Sociedad Española SEIMC. Cumple con la garantía científica de esta Sociedad, la doble función de difundir trabajos de investigación, tanto clínicos como microbiológicos, referidos a la patología infecciosa, y contribuye a la formación continuada de los interesados en aquella patología mediante artículos orientados a ese fin y elaborados por autores de la mayor calificación invitados por la revista.